Exforge and Novalgin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Exforge (amlodipine besylate; valsartan) and Novalgin (metamizole). Common drug interactions include acute myocardial infarction among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Exforge and Novalgin. It is created by eHealthMe based on reports of 72 people who take the same drugs from the FDA, and is updated regularly.

What is Exforge?

Exforge has active ingredients of amlodipine besylate; valsartan. It is often used in high blood pressure. eHealthMe is studying from 13,350 Exforge users. Check the latest studies of Exforge.

What is Novalgin?

Novalgin has active ingredients of metamizole. It is often used in pain. eHealthMe is studying from 10,177 Novalgin users. Check the latest studies of Novalgin.

On Jul, 06, 2026

72 people who take Exforge and Novalgin together, and have interactions are studied.

What are the common drug interactions of Exforge and Novalgin, by gender? *:

female:

Acute myocardial infarction (acute heart attack)
Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
Dermatitis allergic (inflammation of the skin due allergic reaction)
Anaemia (lack of blood)
Cd4 lymphocytes decreased
Chest pain
Decreased appetite
Diarrhoea
Diverticulum intestinal (a pouch that is attached to the first part of the small intestine)
Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)

male:

Anaemia (lack of blood)
Nasopharyngitis (inflammation of the nasopharynx)
Influenza
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Peripheral swelling
Portal vein thrombosis (venous thrombosis affecting the hepatic portal vein)
Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose)
Diarrhoea
Decreased appetite
Oedema peripheral (superficial swelling)

What are the common drug interactions of Exforge and Novalgin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Thrombocytopenia (decrease of platelets in blood)

40-49:

Appendiceal abscess
Appendicitis perforated (perforated appendicitis is a condition in which an inflamed appendix bursts)
Large intestinal ulcer
Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs)
Appendicitis (inflammation of the appendix)

50-59:

Red blood cell count decreased
Rash pustular (redness with pustules)
Ageusia (loss of taste functions of the tongue)
Bone pain
Immunosuppression
Injection site induration
Injection site reaction
Petechiae (a small red or purple spot caused by bleeding into the skin)
Cd4 lymphocytes decreased
Chest pain

60+:

Anaemia (lack of blood)
Thrombocytopenia (decrease of platelets in blood)
Portal vein thrombosis (venous thrombosis affecting the hepatic portal vein)
Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose)
Pyrexia (fever)
Hyperkalaemia (damage to or disease of the kidney)
Tumour lysis syndrome (a group of metabolic complications that can occur after treatment of cancer, these complications are caused by the breakdown products of dying cancer cells)
Leukopenia (less number of white blood cells in blood)
C-reactive protein increased
Febrile neutropenia (fever with reduced white blood cells)

What are the existing conditions these people have? *

High Blood Pressure: 22 people, 30.56%
Metastatic Renal Cell Carcinoma (spreadable kidney cell tumour): 14 people, 19.44%
Reflux Gastritis (a condition in which the lining of a person's stomach becomes inflamed as a result of exposure to bile): 10 people, 13.89%
Renal Cell Carcinoma (a kidney cancer): 8 people, 11.11%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 7 people, 9.72%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 7 people, 9.72%
Osteoporosis (bones weak and more likely to break): 7 people, 9.72%
Rickets (softening of bones): 5 people, 6.94%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 5 people, 6.94%
Depression: 5 people, 6.94%

* Approximation only. Some reports may have incomplete information.

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