Exforge and Nuvigil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Exforge (amlodipine besylate; valsartan) and Nuvigil (armodafinil). Common drug interactions include back pain among females and bladder hypertrophy among males.

The phase IV clinical study analyzes what interactions people have when they take Exforge and Nuvigil. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Exforge?

Exforge has active ingredients of amlodipine besylate; valsartan. It is often used in high blood pressure. eHealthMe is studying from 13,350 Exforge users. Check the latest studies of Exforge.

What is Nuvigil?

Nuvigil has active ingredients of armodafinil. It is often used in narcolepsy. eHealthMe is studying from 23,669 Nuvigil users. Check the latest studies of Nuvigil.

On Jul, 12, 2026

27 people who take Exforge and Nuvigil together, and have interactions are studied.

What are the common drug interactions of Exforge and Nuvigil, by gender? *:

female:

Back pain
Exostosis (formation of new bone on the surface of a bone)
Hypertonic bladder (bladder-storage function that causes a sudden urge to urinate)
Leukopenia (less number of white blood cells in blood)
Uterine polyp (a mass in the inner lining of the uterus)
Hypoaesthesia (reduced sense of touch or sensation)
Intervertebral disc protrusion (spinal disc protrusion)
Nerve root compression
Osteoporosis (bones weak and more likely to break)
Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve)

male:

Bladder hypertrophy (bladder overgrowth- increase in cell size)
Leukocytosis (increased white blood cells)
Ingrown hair
Nausea (feeling of having an urge to vomit)
Pruritus generalised (generalized itching)
Psoriasis (immune-mediated disease that affects the skin)
Sinus disorder (disease of sinus)
Stomatitis (inflammation of mucous membrane of mouth)
Upper-airway cough syndrome
Arthritis (form of joint disorder that involves inflammation of one or more joints)

What are the common drug interactions of Exforge and Nuvigil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Back pain
Nerve root compression
Osteoporosis (bones weak and more likely to break)
Spinal compression fracture (fracture due to spinal compression on bone)
Spinal fracture (fracture in one of vertebrae)
Amyloidosis (a tumour within which amyloid is produced)
Ankle fracture
Blood potassium decreased
Cardiac arrest
Cardiac disorder

50-59:

Bladder hypertrophy (bladder overgrowth- increase in cell size)
Leukocytosis (increased white blood cells)
Depressed level of consciousness
Altered state of consciousness (altered state of mind)

60+:

Exostosis (formation of new bone on the surface of a bone)
Hypertonic bladder (bladder-storage function that causes a sudden urge to urinate)
Adhesion
Dyspepsia (indigestion)
Gastric disorder (disease of stomach)
Injection site pain
Nausea (feeling of having an urge to vomit)
Pain in extremity
Stomatitis (inflammation of mucous membrane of mouth)
Thyroid neoplasm (tumour of thyroid)

What are the existing conditions these people have? *

Cataplexy (loss of muscle tone accompanied by full conscious awareness): 13 people, 48.15%
High Blood Cholesterol: 6 people, 22.22%
High Blood Pressure: 6 people, 22.22%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 18.52%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 4 people, 14.81%
Fibromyalgia (a long-term condition which causes pain all over the body): 4 people, 14.81%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 14.81%
Hair Loss: 4 people, 14.81%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 4 people, 14.81%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 14.81%

* Approximation only. Some reports may have incomplete information.

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