Exforge and Premarin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Exforge (amlodipine besylate; valsartan) and Premarin (estrogens, conjugated). Common drug interactions include drug ineffective among females.

The phase IV clinical study analyzes what interactions people have when they take Exforge and Premarin. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.

What is Exforge?

Exforge has active ingredients of amlodipine besylate; valsartan. It is often used in high blood pressure. eHealthMe is studying from 13,350 Exforge users. Check the latest studies of Exforge.

What is Premarin?

Premarin has active ingredients of estrogens, conjugated. It is often used in hormone replacement therapy. eHealthMe is studying from 99,630 Premarin users. Check the latest studies of Premarin.

On Jul, 23, 2026

32 people who take Exforge and Premarin together, and have interactions are studied.

What are the common drug interactions of Exforge and Premarin, by gender? *:

female:

Drug ineffective
Joint injury
Ear discomfort
Excoriation (to tear or wear off the skin of)
Fall
Gastric disorder (disease of stomach)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hot flush (sudden feelings of heat)
Insomnia (sleeplessness)
Malaise (a feeling of general discomfort or uneasiness)

male:

n/a

What are the common drug interactions of Exforge and Premarin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Drug ineffective
Cough
Dyspepsia (indigestion)
Ear discomfort
Excoriation (to tear or wear off the skin of)
Fall
Gastric disorder (disease of stomach)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Joint injury
Sinus congestion (blockage of sinus)

60+:

Dyspnoea (difficult or laboured respiration)
Gait disturbance
Fatigue (feeling of tiredness)
Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
Hypotension (abnormally low blood pressure)
Insomnia (sleeplessness)
Joint injury
Pain in extremity
Palpitations (feelings or sensations that your heart is pounding or racing)
Pneumonia

What are the existing conditions these people have? *

High Blood Pressure: 10 people, 31.25%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 18.75%
High Blood Cholesterol: 5 people, 15.62%
Fluid Retention (an abnormal accumulation of fluid in the blood): 3 people, 9.38%
Stress And Anxiety: 2 people, 6.25%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 6.25%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 2 people, 6.25%
Pain: 2 people, 6.25%
Osteoporosis (bones weak and more likely to break): 2 people, 6.25%
Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 2 people, 6.25%

* Approximation only. Some reports may have incomplete information.

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