Exidine and Advil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Exidine (chlorhexidine gluconate) and Advil (ibuprofen). Common drug interactions include bronchitis among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Exidine and Advil. It is created by eHealthMe based on reports of 95 people who take the same drugs from the FDA, and is updated regularly.

What is Exidine?

Exidine has active ingredients of chlorhexidine gluconate. eHealthMe is studying from 17,299 Exidine users. Check the latest studies of Exidine.

What is Advil?

Advil has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 62,533 Advil users. Check the latest studies of Advil.

On Jul, 12, 2026

95 people who take Exidine and Advil together, and have interactions are studied.

What are the common drug interactions of Exidine and Advil, by gender? *:

female:

Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Fatigue (feeling of tiredness)
Pleural effusion (water on the lungs)
Abdominal distension
Abdominal pain
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Decreased appetite
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Metastases to bone (cancer spreads to bone)
Vision blurred

male:

Anxiety
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Osteomyelitis (infection of bone)
Osteonecrosis (death of bone)
Pyrexia (fever)
Spinal osteoarthritis (joint cartilage loss in spine)
Bone density decreased
Bone disorder
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Polyp

What are the common drug interactions of Exidine and Advil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Vomiting
Abdominal distension
Abdominal pain upper
Benign lymph node neoplasm (benign (non-cancerous) tumours of the lymph node)
Biliary colic
Cholecystitis chronic (long lasting infection of gallbladder)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Decreased appetite
Diarrhoea
Epigastric discomfort

20-29:

Heparin-induced thrombocytopenia
Acute lung injury
Cardiac arrest
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Disseminated intravascular coagulation (systemic activation of blood coagulation)
Hyperglycaemia (high blood sugar)
Hypotension (abnormally low blood pressure)
Ischaemic hepatitis (decreased blood supply to the liver resulting in injury to liver cells)
Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)
Pyrexia (fever)

30-39:

Dyspnoea (difficult or laboured respiration)
Anxiety
Atelectasis (partial or complete collapse of the lung)
Back pain
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Death
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Metastases to bone (cancer spreads to bone)
Oedema peripheral (superficial swelling)
Osteonecrosis of jaw (death of bone of jaw)

40-49:

Back pain
Depression
Drug ineffective
Fall
Micturition urgency (urgency to pass the urine)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Anxiety
Arthralgia (joint pain)
Ataxia (loss of full control of bodily movements)
Binocular eye movement disorder

50-59:

Alopecia (absence of hair from areas of the body)
Arthralgia (joint pain)
Central nervous system lesion (an abnormality in tissue of brain or spinal cord)
Chronic kidney disease
Emotional distress
Femur fracture
Flank pain (a distressing sensation experienced around the lower back and the upper abdomen)
Heart rate decreased
Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle)
Hypoaesthesia (reduced sense of touch or sensation)

60+:

Osteomyelitis (infection of bone)
Diarrhoea
Bone density decreased
Colon adenoma (non cancerous epithelial colon tumour having a glandular origin and structure)
Coronary angioplasty
Coronary arterial stent insertion
Deformity (disfigurement)
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
Dysphagia (a condition in which swallowing is difficult or painful)
Emotional distress

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 15 people, 15.79%
High Blood Pressure: 11 people, 11.58%
Prostate Cancer: 10 people, 10.53%
Headache (pain in head): 10 people, 10.53%
Nausea (feeling of having an urge to vomit): 9 people, 9.47%
Metastases To Bone (cancer spreads to bone): 7 people, 7.37%
Stress And Anxiety: 6 people, 6.32%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 6.32%
Dyspnea (difficult or laboured breathing): 6 people, 6.32%
Depression: 6 people, 6.32%

* Approximation only. Some reports may have incomplete information.

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