Exidine and Cefpodoxime proxetil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Exidine (chlorhexidine gluconate) and Cefpodoxime proxetil (cefpodoxime proxetil). Common drug interactions include chronic kidney disease among females and acute respiratory distress syndrome among males.

The phase IV clinical study analyzes what interactions people have when they take Exidine and Cefpodoxime proxetil. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Exidine?

Exidine has active ingredients of chlorhexidine gluconate. eHealthMe is studying from 17,299 Exidine users. Check the latest studies of Exidine.

What is Cefpodoxime proxetil?

Cefpodoxime proxetil has active ingredients of cefpodoxime proxetil. eHealthMe is studying from 1,357 Cefpodoxime proxetil users. Check the latest studies of Cefpodoxime proxetil.



On Jul, 17, 2026

24 people who take Exidine and Cefpodoxime proxetil together, and have interactions are studied.

Exidine and Cefpodoxime proxetil drug interactions.

What are the common drug interactions of Exidine and Cefpodoxime Proxetil, by gender? *:

female:

  1. Chronic kidney disease
  2. Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
  3. Erythema (redness of the skin)
  4. Nephrogenic anaemia (anaemia due to kidney disease)
  5. Osteomyelitis (infection of bone)
  6. Renal failure (kidney dysfunction)
  7. Sepsis (a severe blood infection that can lead to organ failure and death)
  8. Sinusitis (inflammation of sinus)
  9. Skin fissures (a crack in the skin)
  10. Anaemia (lack of blood)

male:

  1. Acute respiratory distress syndrome
  2. Apallic syndrome (serious brain damage, when cortical parts of the brain are disconnected from brainstem)
  3. Drug hypersensitivity
  4. Febrile neutropenia (fever with reduced white blood cells)
  5. Plasma cell myeloma (cancer that begins in plasma cells)
  6. Pruritus (severe itching of the skin)
  7. Tooth disorder (tooth disease)
  8. Urticaria (rash of round, red welts on the skin that itch intensely)
  9. Venoocclusive liver disease (small veins in the liver are obstructed)

What are the common drug interactions of Exidine and Cefpodoxime Proxetil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Pruritus (severe itching of the skin)
  2. Urticaria (rash of round, red welts on the skin that itch intensely)

30-39:

n/a

40-49:

  1. Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
  2. Erythema (redness of the skin)
  3. Skin fissures (a crack in the skin)
  4. Anaemia (lack of blood)
  5. Epistaxis (bleed from the nose)
  6. Fatigue (feeling of tiredness)
  7. Neutropenia (an abnormally low number of neutrophils)
  8. Platelet count decreased
  9. Pyrexia (fever)
  10. Rectal haemorrhage (bleeding from anus)

50-59:

  1. Chronic kidney disease
  2. Nephrogenic anaemia (anaemia due to kidney disease)
  3. Renal failure (kidney dysfunction)
  4. Sepsis (a severe blood infection that can lead to organ failure and death)
  5. Osteomyelitis (infection of bone)
  6. Sinusitis (inflammation of sinus)
  7. Acute respiratory distress syndrome
  8. Apallic syndrome (serious brain damage, when cortical parts of the brain are disconnected from brainstem)
  9. Drug hypersensitivity

60+:

  1. Perineal abscess
  2. Febrile neutropenia (fever with reduced white blood cells)
  3. Death
  4. Plasma cell myeloma (cancer that begins in plasma cells)
  5. Tooth disorder (tooth disease)

What are the existing conditions these people have? *

  1. Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 6 people, 25.00%
  2. Head Injury: 5 people, 20.83%
  3. Breast Cancer: 5 people, 20.83%
  4. The Flu (the flu is caused by an influenza virus): 2 people, 8.33%
  5. Pneumonia: 2 people, 8.33%
  6. Nasopharyngitis (inflammation of the nasopharynx): 2 people, 8.33%
  7. Multiple Myeloma (cancer of the plasma cells): 2 people, 8.33%
  8. Infection: 2 people, 8.33%
  9. Hypersensitivity: 2 people, 8.33%
  10. High Blood Cholesterol: 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Exidine and Cefpodoxime proxetil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Exidine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Cefpodoxime proxetil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Exidine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cefpodoxime proxetil and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on chlorhexidine gluconate and cefpodoxime proxetil (the active ingredients of Exidine and Cefpodoxime proxetil, respectively), and Exidine and Cefpodoxime proxetil (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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