Exidine and Pemetrexed drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Exidine (chlorhexidine gluconate) and Pemetrexed (pemetrexed). Common drug interactions include death among females and pneumonitis among males.
The phase IV clinical study analyzes what interactions people have when they take Exidine and Pemetrexed. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.
What is Exidine?
Exidine has active ingredients of chlorhexidine gluconate. eHealthMe is studying from 17,299 Exidine users. Check the latest studies of Exidine.
What is Pemetrexed?
Pemetrexed has active ingredients of pemetrexed. eHealthMe is studying from 17,491 Pemetrexed users. Check the latest studies of Pemetrexed.
32 people who take Exidine and Pemetrexed together, and have interactions are studied.

What are the common drug interactions of Exidine and Pemetrexed, by gender? *:
female:
- Death
- Lung infection
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Anaemia (lack of blood)
- Dizziness
- Pulmonary fibrosis (formation or development of excess fibrous connective tissue (fibrosis) in the lungs)
- Decubitus ulcer (a chronic ulcer of the skin caused by prolonged pressure on it)
- Leukopenia (less number of white blood cells in blood)
- Thrombocytopenia (decrease of platelets in blood)
- Dehydration (dryness resulting from the removal of water)
male:
- Pneumonitis (inflammation of the walls of the alveoli in the lungs)
- Osteonecrosis of jaw (death of bone of jaw)
- Blood calcium decreased
- Blood potassium increased
- Blood sodium decreased
- Diarrhoea
- Escherichia urinary tract infection (urinary tract infection by escherichia coli)
- Granulocyte count increased
- Haemoglobin decreased
- Hypoglycaemia (deficiency of glucose in the bloodstream)
What are the common drug interactions of Exidine and Pemetrexed, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Dehydration (dryness resulting from the removal of water)
- Anaemia (lack of blood)
- Pneumonitis (inflammation of the walls of the alveoli in the lungs)
50-59:
- Anaemia (lack of blood)
- Decubitus ulcer (a chronic ulcer of the skin caused by prolonged pressure on it)
- Leukopenia (less number of white blood cells in blood)
- Pulmonary fibrosis (formation or development of excess fibrous connective tissue (fibrosis) in the lungs)
- Thrombocytopenia (decrease of platelets in blood)
- Drug ineffective
- Malignant neoplasm progression (cancer tumour came back)
- Pulmonary embolism (blockage of the main artery of the lung)
- Pericardial effusion (fluid around the heart)
- Osteonecrosis of jaw (death of bone of jaw)
60+:
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Death
- Blood albumin decreased
- Blood calcium decreased
- Blood potassium increased
- Blood sodium decreased
- Diarrhoea
- Haemoglobin decreased
- Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
- Liver injury
What are the existing conditions these people have? *
- Lung Cancer - Non-Small Cell (lung cancer): 12 people, 37.50%
- Cough: 10 people, 31.25%
- Lung Neoplasm Malignant (cancer tumour of lung): 10 people, 31.25%
- Non-Small Cell Lung Cancer Metastatic (type of epithelial lung cancer spreads to other parts): 7 people, 21.88%
- Nausea And Vomiting: 6 people, 18.75%
- Fever: 6 people, 18.75%
- Fatigue (feeling of tiredness): 6 people, 18.75%
- Constipation: 6 people, 18.75%
- Nausea (feeling of having an urge to vomit): 6 people, 18.75%
- Pain: 5 people, 15.62%
* Approximation only. Some reports may have incomplete information.
Do you take Exidine and Pemetrexed?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Exidine (17,299 reports)
- Pemetrexed (17,491 reports)
Browse all drug interactions of Exidine and Pemetrexed:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Exidine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Pemetrexed:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Exidine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Pemetrexed and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Gota V, Kavathiya K, Doshi K, Gurjar M, Damodaran SE, Noronha V, Joshi A, Prabhash K, "High plasma exposure to pemetrexed leads to severe hyponatremia in patients with advanced non small cell lung cancer receiving pemetrexed-platinum doublet chemotherapy", Cancer management and research, 2017 Jan .
- Gota V, Kavathiya K, Doshi K, Gurjar M, Damodaran SE, Noronha V, Joshi A, Prabhash K, "High plasma exposure to pemetrexed leads to severe hyponatremia in patients with advanced non small cell lung cancer receiving pemetrexed-platinum doublet chemotherapy", Cancer management and research, 2017 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on chlorhexidine gluconate and pemetrexed (the active ingredients of Exidine and Pemetrexed, respectively), and Exidine and Pemetrexed (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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