Exidine and Penlac drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Exidine (chlorhexidine gluconate) and Penlac (ciclopirox). Common drug interactions include decreased interest among females and actinic keratosis among males.

The phase IV clinical study analyzes what interactions people have when they take Exidine and Penlac. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Exidine?

Exidine has active ingredients of chlorhexidine gluconate. eHealthMe is studying from 17,299 Exidine users. Check the latest studies of Exidine.

What is Penlac?

Penlac has active ingredients of ciclopirox. eHealthMe is studying from 492 Penlac users. Check the latest studies of Penlac.

On Aug, 07, 2026

27 people who take Exidine and Penlac together, and have interactions are studied.

What are the common drug interactions of Exidine and Penlac, by gender? *:

female:

Decreased interest
Fall
Femur fracture
General physical health deterioration (weak health status)
Impaired healing
Loose tooth
Osteonecrosis of jaw (death of bone of jaw)
Osteoporosis (bones weak and more likely to break)
Osteoradionecrosis (irradiation of bones causes damage to osteocytes and impairs the blood supply)
Photopsia (presence of perceived flashes of light)

male:

Actinic keratosis (skin disease due to sun exposure)
Adenomyosis (presence of ectopic glandular tissue found in muscle)
Cardiac arrest
Carotid artery stenosis (narrowing of carotid artery)
Cellulitis (infection under the skin)
Cerebral atrophy (decrement in size of brain)
Cervical cyst (mucus-filled cyst on the surface of the cervix)
Chest wall abscess
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Colon adenoma (non cancerous epithelial colon tumour having a glandular origin and structure)

What are the common drug interactions of Exidine and Penlac, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Eustachian tube dysfunction (eustachian tube problems like clearing the ears when flying, suffering infection, and recurring ear infection)
Exposed bone in jaw
Fall
Femur fracture
Foot deformity (functional disability of foot)
General physical health deterioration (weak health status)
Haematoma (collection of blood outside the blood vessels)
Haematuria (presence of blood in urine)
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Hepatic cyst

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Surgery

60+:

Anxiety
Bone disorder
Osteoradionecrosis (irradiation of bones causes damage to osteocytes and impairs the blood supply)
Pain
Photopsia (presence of perceived flashes of light)
Posterior capsule opacification
Skin papilloma (a general medical term for a tumour of the skin or mucous membrane with finger-like projections)
Tooth disorder (tooth disease)
Visual acuity reduced (reduced clearness of vision)
Visual impairment

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 11 people, 40.74%
Pain: 3 people, 11.11%

* Approximation only. Some reports may have incomplete information.

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