Exidine and Revatio drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Exidine (chlorhexidine gluconate) and Revatio (sildenafil citrate). Common drug interactions include erythema among females and cold sweat among males.

The phase IV clinical study analyzes what interactions people have when they take Exidine and Revatio. It is created by eHealthMe based on reports of 29 people who take the same drugs from the FDA, and is updated regularly.

What is Exidine?

Exidine has active ingredients of chlorhexidine gluconate. eHealthMe is studying from 17,299 Exidine users. Check the latest studies of Exidine.

What is Revatio?

Revatio has active ingredients of sildenafil citrate. It is often used in pulmonary hypertension. eHealthMe is studying from 44,849 Revatio users. Check the latest studies of Revatio.

On Jul, 18, 2026

29 people who take Exidine and Revatio together, and have interactions are studied.

What are the common drug interactions of Exidine and Revatio, by gender? *:

female:

Erythema (redness of the skin)
Faeces discoloured
Fatigue (feeling of tiredness)
Foot fracture
Gastric disorder (disease of stomach)
Haematocrit decreased
Haemolysis (breaking open of red blood cells and the release of haemoglobin into the surrounding fluid)
Haptoglobin decreased
Injection site irritation
Device related infection

male:

Cold sweat
Dental caries
Haemorrhage (bleeding)
Hip fracture
Malaise (a feeling of general discomfort or uneasiness)
Skin irritation
Weight decreased
Dacryocanaliculitis (1. inflammation of the lacrimal ducts. 2. inflammation of the lacrimal sac and lacrimal canaliculi)
Oedema peripheral (superficial swelling)
Pulmonary valve disease

What are the common drug interactions of Exidine and Revatio, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Device related infection
Diarrhoea
Epistaxis (bleed from the nose)
Headache (pain in head)
Nausea (feeling of having an urge to vomit)
Oedema peripheral (superficial swelling)
Vomiting
Application site reaction
Arthralgia (joint pain)
Blood disorder

20-29:

Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)

30-39:

n/a

40-49:

Catheter site inflammation (infection at catheter site)
Device related infection
Emergency care
Fluid retention (an abnormal accumulation of fluid in the blood)
Rash erythematous (redness of the skin)
Rash pruritic (redness with itching)
Skin irritation
Adverse event
Haemorrhage (bleeding)
Portal hypertension (increase in the blood pressure within a system of veins called the portal venous system)

50-59:

Arthralgia (joint pain)
Catheter site discharge
Catheter site erythema (redness of skin at catheter site)
Catheter site infection (infection at the site of insertion)
Decreased appetite
Device occlusion
Dyspnoea (difficult or laboured respiration)
Haemorrhage (bleeding)
Hip fracture
Malaise (a feeling of general discomfort or uneasiness)

60+:

Cold sweat
Dental caries
Injection site irritation
Injection site oedema
Injection site pain
Nasopharyngitis (inflammation of the nasopharynx)
Skin disorder (skin disease)
Weight increased
Chronic respiratory failure
Drug ineffective

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 19 people, 65.52%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 6 people, 20.69%
Oedema Peripheral (superficial swelling): 5 people, 17.24%
Thrombosis (formation of a blood clot inside a blood vessel): 4 people, 13.79%
Urination - Excessive Volume: 2 people, 6.90%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 6.90%
Blood Pressure Abnormal: 2 people, 6.90%
Cardiac Failure Congestive: 2 people, 6.90%
Cor Pulmonale Chronic (long lasting enlargement of the right ventricle of the heart): 2 people, 6.90%
Dyspnea (difficult or laboured breathing): 2 people, 6.90%

* Approximation only. Some reports may have incomplete information.

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