Simulect and Exidine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Simulect (basiliximab) and Exidine (chlorhexidine gluconate). Common drug interactions include kidney transplant rejection among females and kidney transplant rejection among males.

The phase IV clinical study analyzes what interactions people have when they take Simulect and Exidine. It is created by eHealthMe based on reports of 9 people who take the same drugs from the FDA, and is updated regularly.

What is Simulect?

Simulect has active ingredients of basiliximab. eHealthMe is studying from 3,861 Simulect users. Check the latest studies of Simulect.

What is Exidine?

Exidine has active ingredients of chlorhexidine gluconate. eHealthMe is studying from 17,299 Exidine users. Check the latest studies of Exidine.

On Jun, 13, 2026

9 people who take Simulect and Exidine together, and have interactions are studied.

What are the common drug interactions of Simulect and Exidine, by gender? *:

female:

Kidney transplant rejection
Renal tubular necrosis (death of kidney tubules)
Arteritis (inflammation of the walls of arteries)
Hepatitis fulminant (life-threatening condition defined by significantly impaired liver function)
Ischaemia (insufficient supply of blood to an organ, usually due to a blocked artery)
Lymphocytic infiltration (lymphocyte deposition)
Plasma cell disorder
Renal tubular acidosis (medical condition that involves an accumulation of acid in the body due to a failure of the kidneys)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Anal fissure

male:

Kidney transplant rejection
Glomerulonephritis (a group of conditions that affect parts of the kidneys called glomeruli)
Bladder dilatation
Blood creatinine decreased
Blood lactate dehydrogenase increased
Blood pressure fluctuation
Haemorrhagic stroke (stroke caused by the rupture of a blood vessel in the brain)
Hyperbilirubinaemia (excess of bilirubin in the blood)
Leukaemoid reaction (elevated white blood cell count, or leukocytosis, that is a physiological response to stress or infection)
Lung disorder (lung disease)

What are the common drug interactions of Simulect and Exidine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Acute pulmonary oedema (sudden deposit of fluid in the lung))
Haemorrhagic stroke (stroke caused by the rupture of a blood vessel in the brain)
Leukaemoid reaction (elevated white blood cell count, or leukocytosis, that is a physiological response to stress or infection)
Lung disorder (lung disease)
Lung infection
Pneumonia
Pulmonary function test decreased

10-19:

n/a

20-29:

n/a

30-39:

Kidney transplant rejection
Arteritis (inflammation of the walls of arteries)
Lymphocytic infiltration (lymphocyte deposition)
Renal tubular necrosis (death of kidney tubules)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Glomerulonephritis (a group of conditions that affect parts of the kidneys called glomeruli)
Ischaemia (insufficient supply of blood to an organ, usually due to a blocked artery)
Plasma cell disorder
Renal tubular acidosis (medical condition that involves an accumulation of acid in the body due to a failure of the kidneys)
Anaemia (lack of blood)

40-49:

Hepatitis fulminant (life-threatening condition defined by significantly impaired liver function)
Anal fissure
Anastomotic leak
Dyschezia (difficulty in defecating)
Graft complication
Kidney transplant rejection
Procedural haemorrhage (procedural bleeding)
Renal tubular necrosis (death of kidney tubules)
Transplant rejection (a transplant material is not worked)
Urinoma (a collection of extravasated urine)

50-59:

n/a

60+:

Arteriovenous fistula
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Proteinuria (presence of protein in the urine)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Vasculitis (inflammation of a blood vessel or blood vessels)
Blood creatinine increased
Capillaritis (inflamed capillaries under the skin)
Glomerulosclerosis (a hardening of the glomerulus in the kidney)
Hypertension (high blood pressure)
Kidney transplant rejection

* Approximation only. Some reports may have incomplete information.

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