Extraneal and Dial drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Extraneal (icodextrin) and Dial (hexachlorophene). Common drug interactions include pneumoperitoneum among females and abdominal pain among males.

The phase IV clinical study analyzes what interactions people have when they take Extraneal and Dial. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Extraneal?

Extraneal has active ingredients of icodextrin. eHealthMe is studying from 32,994 Extraneal users. Check the latest studies of Extraneal.

What is Dial?

Dial has active ingredients of hexachlorophene. eHealthMe is studying from 53 Dial users. Check the latest studies of Dial.

On Jul, 13, 2026

17 people who take Extraneal and Dial together, and have interactions are studied.

What are the common drug interactions of Extraneal and Dial, by gender? *:

female:

Pneumoperitoneum (air or gas in the abdominal (peritoneal) cavity)
Procedural pain
Dysphagia (a condition in which swallowing is difficult or painful)
General physical health deterioration (weak health status)
Hepatotoxicity (chemical-driven liver damage)
Hypersensitivity
Abdominal distension
Abdominal rigidity
Encephalopathy (functioning of the brain is affected by some agent or condition)
Faecal volume increased

male:

Abdominal pain
Peritoneal cloudy effluent
Cardiac failure
Catheter site infection (infection at the site of insertion)
Cerebral haematoma (collection of blood in brain)
Fall
Head injury
Infarction (obstruction of the blood supply to an organ or region of tissue)
Oxygen saturation decreased
Peritonitis bacterial (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs by bacterial)

What are the common drug interactions of Extraneal and Dial, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Abdominal pain
General physical health deterioration (weak health status)
Monocytosis (an increase in the number of monocytes circulating in the blood)
Peritoneal cloudy effluent
Pyrexia (fever)

30-39:

Abdominal pain
Pain
Pneumoperitoneum (air or gas in the abdominal (peritoneal) cavity)

40-49:

Disease recurrence
Peritoneal cloudy effluent

50-59:

Faecal volume increased
Gait disturbance
Monocytosis (an increase in the number of monocytes circulating in the blood)
Peritoneal cloudy effluent
Peritonitis bacterial (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs by bacterial)
Pruritus (severe itching of the skin)

60+:

Anuria (failure of the kidneys to produce urine)
General physical health deterioration (weak health status)
Catheter site infection (infection at the site of insertion)
Fluid retention (an abnormal accumulation of fluid in the blood)
Infarction (obstruction of the blood supply to an organ or region of tissue)
Oxygen saturation decreased
Peritoneal cloudy effluent
Peritonitis bacterial (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs by bacterial)
Staphylococcal infection (an infection with staphylococcus bacteria)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)

What are the existing conditions these people have? *

Ultrafiltration Failure: 1 person, 5.88%
Chronic Renal Failure (kidney failure): 1 person, 5.88%
Cardiac Failure: 1 person, 5.88%
Angiopathy (generic term for a disease of the blood vessels): 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

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