Eylea and Ambien drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Eylea (aflibercept) and Ambien (zolpidem tartrate). Common drug interactions include neuropathy peripheral among females and blindness among males.

The phase IV clinical study analyzes what interactions people have when they take Eylea and Ambien. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Eylea?

Eylea has active ingredients of aflibercept. It is often used in macular degeneration. eHealthMe is studying from 27,868 Eylea users. Check the latest studies of Eylea.

What is Ambien?

Ambien has active ingredients of zolpidem tartrate. It is often used in insomnia. eHealthMe is studying from 93,519 Ambien users. Check the latest studies of Ambien.

On Jul, 13, 2026

19 people who take Eylea and Ambien together, and have interactions are studied.

What are the common drug interactions of Eylea and Ambien, by gender? *:

female:

Neuropathy peripheral (surface nerve damage)
Urinary tract infection
Uveitis (inflammation of the uvea)
Anxiety
Arthralgia (joint pain)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Balance disorder
Blood glucose increased
Blood pressure systolic increased
Chest pain

male:

Blindness
Eye disorder
Eye pain
Vision blurred
Visual impairment
Delusion (a false belief or opinion)
Hallucination (an experience involving the perception of something not present)

What are the common drug interactions of Eylea and Ambien, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Hypertension (high blood pressure)
Uveitis (inflammation of the uvea)
Vision blurred
Visual impairment
Chest pain
Delusion (a false belief or opinion)
Hallucination (an experience involving the perception of something not present)
Mitral valve incompetence (inefficient heart valve)

What are the existing conditions these people have? *

Macular Oedema (fluid and protein deposits collect on or under the macula of the eye (a yellow central area of the retina) and causes it to thicken): 3 people, 15.79%
High Blood Cholesterol: 2 people, 10.53%
Retinal Vessel Occlusion (a blockage in one of the small arteries): 2 people, 10.53%
Dry Eyes (lack of adequate tears): 2 people, 10.53%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 10.53%
Urinary Tract Infection: 1 person, 5.26%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 5.26%
Bladder Disorder: 1 person, 5.26%
Cardiac Failure: 1 person, 5.26%
Diabetic Retinopathy (damage to the retina caused by complications of diabetes): 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

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