Ezetimibe and Hyzaar drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ezetimibe (ezetimibe) and Hyzaar (hydrochlorothiazide; losartan potassium). Common drug interactions include white blood cell count increased among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Ezetimibe and Hyzaar. It is created by eHealthMe based on reports of 50 people who take the same drugs from the FDA, and is updated regularly.

What is Ezetimibe?

Ezetimibe has active ingredients of ezetimibe. It is often used in high blood cholesterol. eHealthMe is studying from 30,849 Ezetimibe users. Check the latest studies of Ezetimibe.

What is Hyzaar?

Hyzaar has active ingredients of hydrochlorothiazide; losartan potassium. It is often used in high blood pressure. eHealthMe is studying from 16,614 Hyzaar users. Check the latest studies of Hyzaar.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

50 people who take Ezetimibe and Hyzaar together, and have interactions are studied.

What are the common drug interactions of Ezetimibe and Hyzaar, by gender? *:

female:

White blood cell count increased
Abdominal discomfort
Alopecia (absence of hair from areas of the body)
Angina pectoris (chest pain due to ischemia of the heart muscle)
Aphasia (damage to the parts of the brain that control language)
Asthma
Blood sodium increased
Breast cyst
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Decreased appetite

male:

Chronic kidney disease
Ingrowing nail
Anaemia (lack of blood)
Cardiac enzymes increased
Cardiac pacemaker replacement
Dehydration (dryness resulting from the removal of water)
Dysphagia (a condition in which swallowing is difficult or painful)
Gastritis erosive (a break in the surface layer of the membrane lining the stomach with infection)
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Hypersensitivity

What are the common drug interactions of Ezetimibe and Hyzaar, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Fatigue (feeling of tiredness)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Cardiac pacemaker replacement
Hypersensitivity
Multiple allergies (allergy to multiple agents)
Pyelonephritis (inflammation of kidney caused by bacteria)
Renal tubular necrosis (death of kidney tubules)
Angina pectoris (chest pain due to ischemia of the heart muscle)
Asthma
Coronary arterial stent insertion

60+:

Nausea (feeling of having an urge to vomit)
Arthralgia (joint pain)
Abasia (inability to walk)
Altered state of consciousness (altered state of mind)
Anaemia (lack of blood)
Anxiety
Asthenia (weakness)
Blood bilirubin decreased
Blood chloride decreased
Blood urea increased

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 8 people, 16.00%
Joint Pain: 7 people, 14.00%
Stress And Anxiety: 6 people, 12.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 12.00%
Pain: 5 people, 10.00%
Diabetes: 5 people, 10.00%
Muscle Spasms (muscle contraction): 4 people, 8.00%
Asthma: 4 people, 8.00%
Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs): 3 people, 6.00%
Chest Pain: 3 people, 6.00%

* Approximation only. Some reports may have incomplete information.

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