Ezetimibe and Lunesta drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Ezetimibe (ezetimibe) and Lunesta (eszopiclone). Common drug interactions include anxiety among females and nephrotic syndrome among males.
The phase IV clinical study analyzes what interactions people have when they take Ezetimibe and Lunesta. It is created by eHealthMe based on reports of 28 people who take the same drugs from the FDA, and is updated regularly.
What is Ezetimibe?
Ezetimibe has active ingredients of ezetimibe. It is often used in high blood cholesterol. eHealthMe is studying from 30,849 Ezetimibe users. Check the latest studies of Ezetimibe.
What is Lunesta?
Lunesta has active ingredients of eszopiclone. It is often used in insomnia. eHealthMe is studying from 26,936 Lunesta users. Check the latest studies of Lunesta.
28 people who take Ezetimibe and Lunesta together, and have interactions are studied.

What are the common drug interactions of Ezetimibe and Lunesta, by gender? *:
female:
- Anxiety
- Fall
- Pulmonary arterial hypertension (high blood pressure in the arteries of lungs)
- Alanine aminotransferase increased
- Aspartate aminotransferase increased
- Blood creatine phosphokinase increased
- Myalgia (muscle pain)
- Pyrexia (fever)
- Urinary tract infection
- Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
male:
- Nephrotic syndrome (kidney disease with proteinuria, hypoalbuminemia, and oedema)
- Abdominal pain upper
- Oxygen saturation decreased
- Blood magnesium decreased
- Chronic kidney disease
- Diarrhoea
- Dry mouth
- Fatigue (feeling of tiredness)
- Malaise (a feeling of general discomfort or uneasiness)
- Metastasis (spreadable cancer to other organ from origin)
What are the common drug interactions of Ezetimibe and Lunesta, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Nephrotic syndrome (kidney disease with proteinuria, hypoalbuminemia, and oedema)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Blood pressure increased
- Bone density decreased
- Chronic kidney disease
- Emotional distress
- Exercise tolerance decreased
- Gait disturbance
- Headache (pain in head)
60+:
- Fall
- Pulmonary arterial hypertension (high blood pressure in the arteries of lungs)
- Abdominal distension
- Constipation
- Decreased appetite
- Diastolic dysfunction
- Dilatation ventricular
- Ejection fraction decreased (systolic heart failure)
- Eye swelling
- Heart rate increased
What are the existing conditions these people have? *
- Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 6 people, 21.43%
- Pain: 5 people, 17.86%
- Constipation: 4 people, 14.29%
- Diabetes: 4 people, 14.29%
- Dry Eyes (lack of adequate tears): 4 people, 14.29%
- Type 2 Diabetes: 4 people, 14.29%
- Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose): 3 people, 10.71%
- Sleep Disorder: 3 people, 10.71%
- Anaemia (lack of blood): 3 people, 10.71%
- Stress And Anxiety: 3 people, 10.71%
* Approximation only. Some reports may have incomplete information.
Do you take Ezetimibe and Lunesta?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Ezetimibe and Lunesta:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Ezetimibe:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Lunesta:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Ezetimibe and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Lunesta and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Lai SW, Lai HC, Lin CL, Liao KF, "Zopiclone use associated with increased risk of acute pancreatitis: a case–control study in Taiwan", International journal of clinical practice, 2015 Nov .
- Lai SW, Lai HC, Lin CL, Liao KF, "Zopiclone use associated with increased risk of acute pancreatitis: a case–control study in Taiwan", International journal of clinical practice, 2015 Nov .
How the study uses the data?
The study uses data from the FDA. It is based on ezetimibe and eszopiclone (the active ingredients of Ezetimibe and Lunesta, respectively), and Ezetimibe and Lunesta (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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