Fanapt and Vistaril drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Fanapt (iloperidone) and Vistaril (hydroxyzine hydrochloride). Common drug interactions include renal injury among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Fanapt and Vistaril. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Fanapt?

Fanapt has active ingredients of iloperidone. It is often used in schizophrenia. eHealthMe is studying from 1,443 Fanapt users. Check the latest studies of Fanapt.

What is Vistaril?

Vistaril has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 9,565 Vistaril users. Check the latest studies of Vistaril.

On Jul, 11, 2026

20 people who take Fanapt and Vistaril together, and have interactions are studied.

What are the common drug interactions of Fanapt and Vistaril, by gender? *:

female:

Renal injury (kidney injury)
Ballismus (violent involuntary rapid and irregular movements)
Choreoathetosis (involuntary movement randomly from one part to another body part)
Dysarthria (speech disorder)
Dyskinesia (abnormality or impairment of voluntary movement)
Dystonia (abnormal muscle tone)
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Musculoskeletal discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves)
Tardive dyskinesia (a disorder that involves involuntary movements)
Tongue disorder (disease of tongue)

male:

Asthenia (weakness)
Skin discolouration (change of skin colour)
Vein discolouration
Retrograde ejaculation (entry of semen into the bladder instead of going out through the urethra during ejaculation)
Ejaculation failure
Completed suicide (act of taking one's own life)
Pericarditis tuberculous (tuberculosis infection of the pericardial membrane (pericardium) covering the heart)
Priapism (prolonged and painful erection that can last from several hours up to a few days)

What are the common drug interactions of Fanapt and Vistaril, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Asthenia (weakness)
Skin discolouration (change of skin colour)
Vein discolouration
Ballismus (violent involuntary rapid and irregular movements)
Choreoathetosis (involuntary movement randomly from one part to another body part)
Dysarthria (speech disorder)
Dyskinesia (abnormality or impairment of voluntary movement)
Dystonia (abnormal muscle tone)
Gait disturbance
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)

30-39:

n/a

40-49:

Decreased appetite
Disturbance in attention
Gait disturbance
Muscle rigidity (muscle stiffness)
Muscular weakness (muscle weakness)
Neuroleptic malignant syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents)
Psychomotor hyperactivity (feelings of extreme restlessness)
Retrograde ejaculation (entry of semen into the bladder instead of going out through the urethra during ejaculation)
Amnestic disorder (group of disorders that involve loss of memories previously established, loss of the ability to create new memories)
Asthenia (weakness)

50-59:

Coma (state of unconsciousness lasting more than six hours)
Hyperglycaemia (high blood sugar)
Pancreatitis (inflammation of pancreas)

60+:

Chronic kidney disease
Renal injury (kidney injury)

What are the existing conditions these people have? *

Schizophrenia, Undifferentiated Type (a type characterized by the presence of prominent psychotic symptoms but not classifiable as catatonic, disorganized, or paranoid): 1 person, 5.00%
Schizoaffective Disorder (a mental disorder characterized by disordered thought): 1 person, 5.00%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 1 person, 5.00%
Pain: 1 person, 5.00%
High Blood Cholesterol: 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

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