Febuxostat and Baclofen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Febuxostat (febuxostat) and Baclofen (baclofen). Common drug interactions include fall among females and vomiting among males.

The phase IV clinical study analyzes what interactions people have when they take Febuxostat and Baclofen. It is created by eHealthMe based on reports of 43 people who take the same drugs from the FDA, and is updated regularly.

What is Febuxostat?

Febuxostat has active ingredients of febuxostat. eHealthMe is studying from 9,693 Febuxostat users. Check the latest studies of Febuxostat.

What is Baclofen?

Baclofen has active ingredients of baclofen. It is often used in muscle spasms. eHealthMe is studying from 108,662 Baclofen users. Check the latest studies of Baclofen.



On Jul, 08, 2026

43 people who take Febuxostat and Baclofen together, and have interactions are studied.

Febuxostat and Baclofen drug interactions.

What are the common drug interactions of Febuxostat and Baclofen, by gender? *:

female:

  1. Fall
  2. Blood pressure increased
  3. Headache (pain in head)
  4. Malaise (a feeling of general discomfort or uneasiness)
  5. Staphylococcal infection (an infection with staphylococcus bacteria)
  6. Viral infection
  7. Cellulitis (infection under the skin)
  8. Gastrointestinal disorder (functional problems of gastrointestinal tract)
  9. Weight fluctuation
  10. Ascites (accumulation of fluid in the abdominal cavity)

male:

  1. Vomiting
  2. Nausea (feeling of having an urge to vomit)
  3. Myositis (inflammation of the muscles)
  4. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  5. Myoclonic epilepsy (type of epilepsy with quick little jerks of the arms, shoulder, or occasionally the legs)
  6. Anal abscess
  7. Vertigo
  8. Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
  9. Oedema peripheral (superficial swelling)
  10. Asthenia (weakness)

What are the common drug interactions of Febuxostat and Baclofen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Alopecia (absence of hair from areas of the body)
  2. Arthralgia (joint pain)
  3. Diarrhoea
  4. Fatigue (feeling of tiredness)
  5. Hypoaesthesia (reduced sense of touch or sensation)
  6. Migraine (headache)
  7. Nausea (feeling of having an urge to vomit)
  8. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  9. Vomiting
  10. Vertigo

40-49:

  1. Abdominal pain
  2. Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
  3. Nausea (feeling of having an urge to vomit)
  4. Pyrexia (fever)
  5. Vomiting

50-59:

  1. Myositis (inflammation of the muscles)
  2. Myoclonic epilepsy (type of epilepsy with quick little jerks of the arms, shoulder, or occasionally the legs)
  3. Anal abscess
  4. Drug hypersensitivity
  5. Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)

60+:

  1. Pericardial effusion (fluid around the heart)
  2. Pneumonia
  3. Fatigue (feeling of tiredness)
  4. Intestinal obstruction
  5. Aphasia (damage to the parts of the brain that control language)
  6. Arrhythmia (irregular heartbeat)
  7. Asthenia (weakness)
  8. Bacteraemia (presence of bacteria in the blood)
  9. Blood potassium decreased
  10. Cardiac failure congestive

What are the existing conditions these people have? *

  1. Pain: 10 people, 23.26%
  2. Anaemia (lack of blood): 7 people, 16.28%
  3. Gout (uric acid crystals building up in the body): 7 people, 16.28%
  4. Constipation: 7 people, 16.28%
  5. Hiccups (an involuntary spasm of the diaphragm and respiratory organs, with a sudden closure of the glottis and a sound like a cough): 6 people, 13.95%
  6. Hypokalemia (low potassium): 6 people, 13.95%
  7. Immunodeficiency Common Variable: 6 people, 13.95%
  8. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 9.30%
  9. Nausea (feeling of having an urge to vomit): 4 people, 9.30%
  10. Hyperuricaemia (level of uric acid in the blood that is abnormally high): 4 people, 9.30%

* Approximation only. Some reports may have incomplete information.

Do you take Febuxostat and Baclofen?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Febuxostat and Baclofen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Febuxostat:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Baclofen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Febuxostat and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Baclofen and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on febuxostat and baclofen (the active ingredients of Febuxostat and Baclofen, respectively), and Febuxostat and Baclofen (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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