Febuxostat and Captopril drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Febuxostat (febuxostat) and Captopril (captopril). Common drug interactions include chronic kidney disease among females and heparin-induced thrombocytopenia among males.

The phase IV clinical study analyzes what interactions people have when they take Febuxostat and Captopril. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Febuxostat?

Febuxostat has active ingredients of febuxostat. eHealthMe is studying from 9,693 Febuxostat users. Check the latest studies of Febuxostat.

What is Captopril?

Captopril has active ingredients of captopril. It is often used in high blood pressure. eHealthMe is studying from 17,438 Captopril users. Check the latest studies of Captopril.

On Aug, 08, 2026

11 people who take Febuxostat and Captopril together, and have interactions are studied.

Febuxostat and Captopril drug interactions.

What are the common drug interactions of Febuxostat and Captopril, by gender? *:

female:

Chronic kidney disease
Interstitial lung disease
Nephrogenic anaemia (anaemia due to kidney disease)
Renal tubular necrosis (death of kidney tubules)
Chills (felling of cold)
Myalgia (muscle pain)
Nausea (feeling of having an urge to vomit)
Pyrexia (fever)
Renal failure (kidney dysfunction)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)

male:

Heparin-induced thrombocytopenia
Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
Dysarthria (speech disorder)
Electrocardiogram st segment depression
Hyperuricaemia (level of uric acid in the blood that is abnormally high)
Peripheral arterial occlusive disease (reproducible ischemic muscle pain)
Restless legs syndrome (a powerful urge to move your legs)
Schizophrenia (a mental disorder characterized by a breakdown of thought processes)
Sepsis (a severe blood infection that can lead to organ failure and death)
Troponin increased

What are the common drug interactions of Febuxostat and Captopril, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Heparin-induced thrombocytopenia
Pyrexia (fever)
Acute myocardial infarction (acute heart attack)
Cardiac failure congestive
Chills (felling of cold)
Drug level increased
Electrocardiogram st segment depression
Myalgia (muscle pain)
Nausea (feeling of having an urge to vomit)
Renal failure (kidney dysfunction)

What are the existing conditions these people have? *

Gout (uric acid crystals building up in the body): 6 people, 54.55%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 45.45%
High Blood Cholesterol: 5 people, 45.45%
Cardiac Disorder: 3 people, 27.27%
Depression: 3 people, 27.27%
Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 27.27%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 2 people, 18.18%
Arrhythmias (irregular heartbeat): 2 people, 18.18%
B Precursor Type Acute Leukaemia (lymphoid cancer): 2 people, 18.18%
Bacterial Infection: 2 people, 18.18%

* Approximation only. Some reports may have incomplete information.

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