Febuxostat and Imdur drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Febuxostat (febuxostat) and Imdur (isosorbide mononitrate). Common drug interactions include acute respiratory failure among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Febuxostat and Imdur. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Febuxostat?

Febuxostat has active ingredients of febuxostat. eHealthMe is studying from 9,693 Febuxostat users. Check the latest studies of Febuxostat.

What is Imdur?

Imdur has active ingredients of isosorbide mononitrate. It is often used in angina. eHealthMe is studying from 17,367 Imdur users. Check the latest studies of Imdur.



On Jul, 05, 2026

17 people who take Febuxostat and Imdur together, and have interactions are studied.

Febuxostat and Imdur drug interactions.

What are the common drug interactions of Febuxostat and Imdur, by gender? *:

female:

  1. Acute respiratory failure
  2. Pneumonia
  3. Thrombosis (formation of a blood clot inside a blood vessel)
  4. Upper gastrointestinal haemorrhage (upper gastrointestinal bleeding)
  5. Arteriovenous fistula occlusion
  6. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  7. Coronary artery stenosis (narrowing of coronary artery)
  8. Dyspnoea (difficult or laboured respiration)
  9. Fluid overload (too much fluid in the blood)
  10. Hypoaesthesia (reduced sense of touch or sensation)

male:

  1. Pneumonia
  2. Heparin-induced thrombocytopenia
  3. Flatulence (flatus expelled through the anus)
  4. Haemoglobin decreased
  5. Headache (pain in head)
  6. Oropharyngeal pain
  7. Sepsis (a severe blood infection that can lead to organ failure and death)
  8. Thrombosis (formation of a blood clot inside a blood vessel)
  9. Vertigo
  10. Bursa disorder

What are the common drug interactions of Febuxostat and Imdur, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

  1. Pneumonia
  2. Heparin-induced thrombocytopenia
  3. Gingival bleeding (bleeding gums)
  4. Haematuria (presence of blood in urine)
  5. Leukocytosis (increased white blood cells)
  6. Muscular weakness (muscle weakness)
  7. Nephrogenic anaemia (anaemia due to kidney disease)
  8. Neutrophilia
  9. Productive cough
  10. Renal failure (kidney dysfunction)

What are the existing conditions these people have? *

  1. High Blood Pressure: 4 people, 23.53%
  2. Gout (uric acid crystals building up in the body): 4 people, 23.53%
  3. Hyperuricaemia (level of uric acid in the blood that is abnormally high): 4 people, 23.53%
  4. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 17.65%
  5. Stable Angina (a constant chest pain): 3 people, 17.65%
  6. Seasonal Allergy (allergic condition due to certain season): 3 people, 17.65%
  7. Primary Myelofibrosis (primary disorder of the bone marrow): 2 people, 11.76%
  8. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 11.76%
  9. High Blood Cholesterol: 2 people, 11.76%
  10. Pain: 2 people, 11.76%

* Approximation only. Some reports may have incomplete information.

Do you take Febuxostat and Imdur?

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- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Febuxostat and Imdur:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Febuxostat:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Imdur:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Febuxostat and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Imdur and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on febuxostat and isosorbide mononitrate (the active ingredients of Febuxostat and Imdur, respectively), and Febuxostat and Imdur (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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