Febuxostat and Xospata drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Febuxostat (febuxostat) and Xospata (gilteritinib). Common drug interactions include pyrexia among females and pyrexia among males.

The phase IV clinical study analyzes what interactions people have when they take Febuxostat and Xospata. It is created by eHealthMe based on reports of 29 people who take the same drugs from the FDA, and is updated regularly.

What is Febuxostat?

Febuxostat has active ingredients of febuxostat. eHealthMe is studying from 9,693 Febuxostat users. Check the latest studies of Febuxostat.

What is Xospata?

Xospata has active ingredients of gilteritinib. eHealthMe is studying from 2,411 Xospata users. Check the latest studies of Xospata.

On Aug, 06, 2026

29 people who take Febuxostat and Xospata together, and have interactions are studied.

Febuxostat and Xospata drug interactions.

What are the common drug interactions of Febuxostat and Xospata, by gender? *:

female:

Pyrexia (fever)
Drug level increased
Fibrin degradation products increased
Acute myeloid leukaemia recurrent (acute cancer in which the bone marrow makes abnormal myeloblast- recurrent)
Blood creatine phosphokinase increased
Drug eruption (adverse drug reaction of the skin)
Dysphagia (a condition in which swallowing is difficult or painful)
Insomnia (sleeplessness)
Performance status decreased
Renal impairment (severely reduced kidney function)

male:

Pyrexia (fever)
Platelet count decreased
C-reactive protein increased
Dacryocystitis (inflammation of the lacrimal sac causing obstruction of the tube draining tears into the nose)
Myalgia (muscle pain)
Pingueculitis (disorder of eye)
Rash
Myelosuppression (a decrease in the production of blood cells)
Amylase increased
Lipase increased

What are the common drug interactions of Febuxostat and Xospata, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Hospitalisation

50-59:

Blood creatine phosphokinase increased
Pyrexia (fever)
C-reactive protein increased
Dacryocystitis (inflammation of the lacrimal sac causing obstruction of the tube draining tears into the nose)
Myalgia (muscle pain)
Pingueculitis (disorder of eye)
Pneumonia
Rash
Renal impairment (severely reduced kidney function)
Platelet count decreased

60+:

Pyrexia (fever)
Platelet count decreased
Blood creatine phosphokinase increased
Drug level increased
Fibrin degradation products increased
Lipase increased
Pancreatitis (inflammation of pancreas)
Renal impairment (severely reduced kidney function)
Infection
Acute myeloid leukaemia recurrent (acute cancer in which the bone marrow makes abnormal myeloblast- recurrent)

What are the existing conditions these people have? *

Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 19 people, 65.52%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 10 people, 34.48%
Acute Myeloid Leukaemia Recurrent (acute cancer in which the bone marrow makes abnormal myeloblast- recurrent): 9 people, 31.03%
Fever: 8 people, 27.59%
High Blood Pressure: 7 people, 24.14%
Pneumonia: 4 people, 13.79%
Constipation: 4 people, 13.79%
Tumor Lysis Syndrome: 3 people, 10.34%
Acute Febrile Neutrophilic Dermatosis (skin disease characterized by the sudden onset of fever, leukocytosis, and tender): 3 people, 10.34%
Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 3 people, 10.34%

* Approximation only. Some reports may have incomplete information.

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