Fentanyl-100 and Estrace drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Fentanyl-100 (fentanyl) and Estrace (estradiol). Common drug interactions include depression among females.

The phase IV clinical study analyzes what interactions people have when they take Fentanyl-100 and Estrace. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Fentanyl-100?

Fentanyl-100 has active ingredients of fentanyl. It is often used in pain. eHealthMe is studying from 7,047 Fentanyl-100 users. Check the latest studies of Fentanyl-100.

What is Estrace?

Estrace has active ingredients of estradiol. It is often used in hormone replacement therapy. eHealthMe is studying from 16,703 Estrace users. Check the latest studies of Estrace.

On Aug, 03, 2026

11 people who take Fentanyl-100 and Estrace together, and have interactions are studied.

Fentanyl-100 and Estrace drug interactions.

What are the common drug interactions of Fentanyl-100 and Estrace, by gender? *:

female:

Depression
Decreased appetite
Intervertebral disc protrusion (spinal disc protrusion)
Synovial cyst (cyst of joint filled with synovial fluid)
Upper respiratory tract infection
Abdominal pain upper
Acquired porphyria (group of disorders that result in a build up of chemicals called porphyrins in the body)
Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
Anaemia (lack of blood)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)

male:

n/a

What are the common drug interactions of Fentanyl-100 and Estrace, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Application site rash
Decreased appetite
Dysphonia (speech disorder attributable to a disorder of phonation)
Insomnia (sleeplessness)
Oedema peripheral (superficial swelling)
Pruritus generalised (generalized itching)
Rash
Tongue blistering

40-49:

Drug abuse

50-59:

Balance disorder
Blood cholesterol increased
Blood pressure increased
Breast cancer stage iii
Cardiac disorder
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Depression
Endolymphatic hydrops (disorder of the inner ear)
Enterocolitis (inflammation of the digestive tract, involving enteritis of the small intestine and colitis of the colon)
Epstein-barr viraemia

60+:

Depression
Breast cancer
Anaemia (lack of blood)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
Asthma
Bacteraemia (presence of bacteria in the blood)
Blood glucose increased
Bone disorder

What are the existing conditions these people have? *

Stress And Anxiety: 6 people, 54.55%
Menopause (end of monthly cycles in women): 6 people, 54.55%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 5 people, 45.45%
Meniere's Disease (a disorder of the inner ear that can affect hearing and balance to a varying degree): 5 people, 45.45%
High Blood Cholesterol: 5 people, 45.45%
Herpes Virus Infection: 5 people, 45.45%
Cardiac Disorder: 5 people, 45.45%
Depression: 4 people, 36.36%
Itching: 1 person, 9.09%
Insomnia (sleeplessness): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

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