Fentanyl citrate and Aredia drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Fentanyl citrate (fentanyl citrate) and Aredia (pamidronate disodium). Common drug interactions include anxiety among females and osteonecrosis of jaw among males.

The phase IV clinical study analyzes what interactions people have when they take Fentanyl citrate and Aredia. It is created by eHealthMe based on reports of 91 people who take the same drugs from the FDA, and is updated regularly.

What is Fentanyl citrate?

Fentanyl citrate has active ingredients of fentanyl citrate. It is often used in pain. eHealthMe is studying from 21,294 Fentanyl citrate users. Check the latest studies of Fentanyl citrate.

What is Aredia?

Aredia has active ingredients of pamidronate disodium. It is often used in breast cancer. eHealthMe is studying from 15,365 Aredia users. Check the latest studies of Aredia.



On Aug, 13, 2026

91 people who take Fentanyl citrate and Aredia together, and have interactions are studied.

Fentanyl citrate and Aredia drug interactions.

What are the common drug interactions of Fentanyl Citrate and Aredia, by gender? *:

female:

  1. Anxiety
  2. Spinal osteoarthritis (joint cartilage loss in spine)
  3. Dyspnoea (difficult or laboured respiration)
  4. Osteomyelitis (infection of bone)
  5. Injury
  6. Back pain
  7. Mouth ulceration (mouth ulcers)
  8. Metastases to bone (cancer spreads to bone)
  9. Pyrexia (fever)
  10. Compression fracture (fracture due to pressure caused by injury)

male:

  1. Osteonecrosis of jaw (death of bone of jaw)
  2. Back pain
  3. Pain in jaw
  4. Spinal osteoarthritis (joint cartilage loss in spine)
  5. Diarrhoea
  6. Hypertension (high blood pressure)
  7. Pneumonia
  8. Tooth abscess (pus formation in tooth)
  9. Compression fracture (fracture due to pressure caused by injury)
  10. General physical health deterioration (weak health status)

What are the common drug interactions of Fentanyl Citrate and Aredia, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Dry mouth
  2. Intervertebral disc degeneration (spinal disc degeneration)
  3. Intervertebral disc protrusion (spinal disc protrusion)
  4. Lumbar radiculopathy (radicular pain in the low back and legs)
  5. Osteoarthritis (a joint disease caused by cartilage loss in a joint)
  6. Osteomyelitis (infection of bone)
  7. Osteonecrosis of jaw (death of bone of jaw)
  8. Abdominal pain
  9. Alveolar osteitis (complication of wound healing following extraction of a tooth)
  10. Anaemia (lack of blood)

40-49:

  1. Anaemia (lack of blood)
  2. Anxiety
  3. Back pain
  4. Impaired healing
  5. Metastases to bone (cancer spreads to bone)
  6. Osteoarthritis (a joint disease caused by cartilage loss in a joint)
  7. Pyrexia (fever)
  8. Bone disorder
  9. Depression
  10. Nausea (feeling of having an urge to vomit)

50-59:

  1. Decreased appetite
  2. Dyspnoea (difficult or laboured respiration)
  3. Hypoaesthesia (reduced sense of touch or sensation)
  4. Infection
  5. Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
  6. Back pain
  7. Cellulitis (infection under the skin)
  8. Injury
  9. Insomnia (sleeplessness)
  10. Neck pain

60+:

  1. Bone disorder
  2. Osteonecrosis of jaw (death of bone of jaw)
  3. Jaw disorder (jaw disease)
  4. Diarrhoea
  5. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  6. Jaw fracture
  7. Osteoporosis (bones weak and more likely to break)
  8. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  9. Oral disorder (mouth disease)
  10. Periodontal disease (disease that attacks the gum and bone and around the teeth)

What are the existing conditions these people have? *

  1. Metastases To Bone (cancer spreads to bone): 29 people, 31.87%
  2. Multiple Myeloma (cancer of the plasma cells): 26 people, 28.57%
  3. Urticaria Pigmentosa (skin disease that produces patches of darker skin (lesions) and very bad itching): 8 people, 8.79%
  4. Osteoporosis (bones weak and more likely to break): 7 people, 7.69%
  5. High Blood Pressure: 7 people, 7.69%
  6. High Blood Cholesterol: 7 people, 7.69%
  7. Breast Cancer Metastatic: 6 people, 6.59%

* Approximation only. Some reports may have incomplete information.

Do you take Fentanyl citrate and Aredia?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Fentanyl citrate and Aredia:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Fentanyl citrate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Aredia:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Fentanyl citrate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Aredia and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on fentanyl citrate and pamidronate disodium (the active ingredients of Fentanyl citrate and Aredia, respectively), and Fentanyl citrate and Aredia (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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