Fentanyl citrate and Pramine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Fentanyl citrate (fentanyl citrate) and Pramine (imipramine hydrochloride). Common drug interactions include narcotic intoxication among females and sepsis among males.

The phase IV clinical study analyzes what interactions people have when they take Fentanyl citrate and Pramine. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Fentanyl citrate?

Fentanyl citrate has active ingredients of fentanyl citrate. It is often used in pain. eHealthMe is studying from 21,294 Fentanyl citrate users. Check the latest studies of Fentanyl citrate.

What is Pramine?

Pramine has active ingredients of imipramine hydrochloride. eHealthMe is studying from 7,461 Pramine users. Check the latest studies of Pramine.



On Jul, 11, 2026

14 people who take Fentanyl citrate and Pramine together, and have interactions are studied.

Fentanyl citrate and Pramine drug interactions.

What are the common drug interactions of Fentanyl Citrate and Pramine, by gender? *:

female:

  1. Narcotic intoxication (a condition caused by use of narcotic agents)
  2. Drug administration error
  3. Obesity (having too much body fat)
  4. Acute respiratory distress syndrome
  5. Agitation (state of anxiety or nervous excitement)
  6. Blood urea increased
  7. Bone marrow failure
  8. Cardiac arrest
  9. Constipation
  10. Dizziness

male:

  1. Sepsis (a severe blood infection that can lead to organ failure and death)
  2. Septic shock (shock due to blood infection)
  3. Ischaemic hepatitis (decreased blood supply to the liver resulting in injury to liver cells)
  4. Leukocytosis (increased white blood cells)
  5. Metabolic encephalopathy (disorder or disease of the brain due to the body's disability to use energy)
  6. Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
  7. Pulmonary oedema (fluid accumulation in the lungs)
  8. Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
  9. Chronic kidney disease
  10. Drug abuse

What are the common drug interactions of Fentanyl Citrate and Pramine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Respiratory disorder (respiratory disease)

20-29:

n/a

30-39:

  1. Narcotic intoxication (a condition caused by use of narcotic agents)
  2. Acute respiratory distress syndrome
  3. Agitation (state of anxiety or nervous excitement)
  4. Blood urea increased
  5. Bone marrow failure
  6. Cardiac arrest
  7. Constipation
  8. Dizziness
  9. Drug abuse
  10. Infection

40-49:

  1. Obesity (having too much body fat)
  2. Drug abuse
  3. Drug dependence
  4. Muscle spasms (muscle contraction)
  5. Tremor (trembling or shaking movements in one or more parts of your body)
  6. Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)

50-59:

  1. Drug administration error

60+:

  1. Sepsis (a severe blood infection that can lead to organ failure and death)
  2. Septic shock (shock due to blood infection)
  3. Ischaemic hepatitis (decreased blood supply to the liver resulting in injury to liver cells)
  4. Leukocytosis (increased white blood cells)
  5. Metabolic encephalopathy (disorder or disease of the brain due to the body's disability to use energy)
  6. Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
  7. Pulmonary oedema (fluid accumulation in the lungs)
  8. Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
  9. Chronic kidney disease
  10. Hepatitis acute

What are the existing conditions these people have? *

  1. Chest Pain: 3 people, 21.43%
  2. Nausea (feeling of having an urge to vomit): 3 people, 21.43%
  3. Herpes Zoster: 2 people, 14.29%
  4. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 14.29%
  5. Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 1 person, 7.14%
  6. Hearing Loss: 1 person, 7.14%
  7. Gastrointestinal Disorder (functional problems of gastrointestinal tract): 1 person, 7.14%
  8. Drowsiness: 1 person, 7.14%
  9. Diabetes: 1 person, 7.14%
  10. Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Fentanyl citrate and Pramine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Fentanyl citrate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Pramine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Fentanyl citrate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Pramine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on fentanyl citrate and imipramine hydrochloride (the active ingredients of Fentanyl citrate and Pramine, respectively), and Fentanyl citrate and Pramine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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