Fentanyl citrate and Roxicet drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Fentanyl citrate (fentanyl citrate) and Roxicet (acetaminophen; oxycodone hydrochloride). Common drug interactions include hypotension among females and dependence among males.

The phase IV clinical study analyzes what interactions people have when they take Fentanyl citrate and Roxicet. It is created by eHealthMe based on reports of 25 people who take the same drugs from the FDA, and is updated regularly.

What is Fentanyl citrate?

Fentanyl citrate has active ingredients of fentanyl citrate. It is often used in pain. eHealthMe is studying from 21,294 Fentanyl citrate users. Check the latest studies of Fentanyl citrate.

What is Roxicet?

Roxicet has active ingredients of acetaminophen; oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 2,254 Roxicet users. Check the latest studies of Roxicet.

On Jul, 09, 2026

25 people who take Fentanyl citrate and Roxicet together, and have interactions are studied.

Fentanyl citrate and Roxicet drug interactions.

What are the common drug interactions of Fentanyl Citrate and Roxicet, by gender? *:

female:

Hypotension (abnormally low blood pressure)
Hysterectomy
Impaired healing
Infection
Inflammation
Insomnia (sleeplessness)
Jaw fracture
Joint crepitation
Joint dislocation (a joint position is changed from normal position)
Klebsiella infection

male:

Dependence
Narcotic intoxication (a condition caused by use of narcotic agents)
Ischaemic hepatitis (decreased blood supply to the liver resulting in injury to liver cells)
Neutropenia (an abnormally low number of neutrophils)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Productive cough
Pyrexia (fever)
Anxiety
Chills (felling of cold)
Depression

What are the common drug interactions of Fentanyl Citrate and Roxicet, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Abdominal pain upper
Anal fissure
Back pain
Biliary colic
Cholecystitis chronic (long lasting infection of gallbladder)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Diarrhoea
Dizziness
Drug ineffective
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)

30-39:

n/a

40-49:

Delirium (wild excitement)
Device related infection
Febrile neutropenia (fever with reduced white blood cells)
Hepatic failure (liver failure)
Hepatitis viral
Ischaemic hepatitis (decreased blood supply to the liver resulting in injury to liver cells)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Hypotension (abnormally low blood pressure)
Infection
Transaminases increased

50-59:

Soft tissue disorder (disease of soft tissue)
Spinal compression fracture (fracture due to spinal compression on bone)
Streptococcal sepsis (whole body inflammation by streptococcal)
Swelling face
Thrombocytopenia (decrease of platelets in blood)
Tongue ulceration (ulcers on tongue)
Tricuspid valve incompetence (inefficient heart valve)
Narcotic intoxication (a condition caused by use of narcotic agents)
Abscess neck (neck abscesses)
Addison's disease (addison's disease, a hormonal disorder disease)

60+:

Pyrexia (fever)
Confusional state
Discomfort
Drug dependence
Dyspepsia (indigestion)
Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
Hospitalisation
International normalised ratio increased
Nausea (feeling of having an urge to vomit)
Respiratory syncytial virus infection (viral disease of respiratory system)

What are the existing conditions these people have? *

Procedural Pain: 4 people, 16.00%
Oropharyngeal Pain: 4 people, 16.00%
Cancer - Throat Or Larynx: 2 people, 8.00%

* Approximation only. Some reports may have incomplete information.

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