Fentanyl and Byetta drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Fentanyl (fentanyl citrate) and Byetta (exenatide synthetic). Common drug interactions include infection among females and pancreatic carcinoma metastatic among males.

The phase IV clinical study analyzes what interactions people have when they take Fentanyl and Byetta. It is created by eHealthMe based on reports of 82 people who take the same drugs from the FDA, and is updated regularly.

What is Fentanyl?

Fentanyl has active ingredients of fentanyl citrate. It is often used in pain. eHealthMe is studying from 73,301 Fentanyl users. Check the latest studies of Fentanyl.

What is Byetta?

Byetta has active ingredients of exenatide synthetic. It is often used in diabetes. eHealthMe is studying from 60,818 Byetta users. Check the latest studies of Byetta.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 03, 2026

82 people who take Fentanyl and Byetta together, and have interactions are studied.

Fentanyl and Byetta drug interactions.

What are the common drug interactions of Fentanyl and Byetta, by gender? *:

female:

  1. Infection
  2. Metastases to peritoneum (cancer spreads to peritoneum)
  3. Renal injury (kidney injury)
  4. Thyroid neoplasm (tumour of thyroid)
  5. Hypophagia (reduced food intake)
  6. Injection site pain
  7. Jaundice cholestatic
  8. Malaise (a feeling of general discomfort or uneasiness)
  9. Nausea (feeling of having an urge to vomit)
  10. Ovarian cancer metastatic (cancer of ovary spreads to other organ or parts)

male:

  1. Pancreatic carcinoma metastatic (pancreatic cancer- metastatic)
  2. Jaundice cholestatic
  3. Bladder neck obstruction (a condition in which the bladder neck does not open appropriately or completely during voiding)
  4. Metastases to lymph nodes (cancer spreads to lymph node)
  5. Prostate cancer metastatic
  6. Pulmonary embolism (blockage of the main artery of the lung)
  7. Metastases to pleura (cancer spreads to pleura)
  8. Respiratory failure (inadequate gas exchange by the respiratory system)
  9. Spondylitis (an inflammation of the vertebra with spinal cord involvement)
  10. Alveolitis allergic (inflammation of the alveoli within the lung caused by hypersensitivity to inhaled organic dusts)

What are the common drug interactions of Fentanyl and Byetta, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Drug ineffective

20-29:

n/a

30-39:

  1. Benign neoplasm of adrenal gland (benign (non-cancerous) tumours of the adrenal gland)
  2. Breast mass
  3. Papillary thyroid cancer
  4. Pituitary tumour benign
  5. Pulmonary mass
  6. Secondary hypothyroidism (pituitary gland and its failure to secrete tsh)
  7. Blood glucose decreased
  8. Blood glucose increased
  9. Fall
  10. Head injury

40-49:

  1. Pancreatitis (inflammation of pancreas)
  2. Fall
  3. Ascites (accumulation of fluid in the abdominal cavity)
  4. Breast abscess
  5. Breast mass
  6. Colorectal cancer (colon cancer or bowel cancer)
  7. Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
  8. Metastases to liver (cancer spreads to liver)
  9. Metastases to lung (cancer spreads to lung)
  10. Metastases to peritoneum (cancer spreads to peritoneum)

50-59:

  1. Diarrhoea
  2. Drug hypersensitivity
  3. Dyspepsia (indigestion)
  4. External ear pain
  5. Eye pain
  6. Food poisoning (poison in food)
  7. Herpes zoster
  8. Hypophagia (reduced food intake)
  9. Infection
  10. Injection site mass

60+:

  1. Pancreatic carcinoma metastatic (pancreatic cancer- metastatic)
  2. Metastases to liver (cancer spreads to liver)
  3. Thyroid neoplasm (tumour of thyroid)
  4. Duodenal ulcer
  5. Gait disturbance
  6. Memory impairment
  7. Psoriasis (immune-mediated disease that affects the skin)
  8. Pyrexia (fever)
  9. Renal injury (kidney injury)
  10. Bladder neck obstruction (a condition in which the bladder neck does not open appropriately or completely during voiding)

What are the existing conditions these people have? *

  1. Type 2 Diabetes: 30 people, 36.59%
  2. High Blood Pressure: 11 people, 13.41%
  3. Nausea (feeling of having an urge to vomit): 8 people, 9.76%
  4. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 8.54%
  5. Thyroid Diseases: 5 people, 6.10%
  6. High Blood Cholesterol: 5 people, 6.10%

* Approximation only. Some reports may have incomplete information.

Do you take Fentanyl and Byetta?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Fentanyl and Byetta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Fentanyl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Byetta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Fentanyl and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Byetta and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on fentanyl citrate and exenatide synthetic (the active ingredients of Fentanyl and Byetta, respectively), and Fentanyl and Byetta (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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