Fentanyl and Daliresp drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Fentanyl (fentanyl citrate) and Daliresp (roflumilast). Common drug interactions include somnolence among females and death among males.

The phase IV clinical study analyzes what interactions people have when they take Fentanyl and Daliresp. It is created by eHealthMe based on reports of 28 people who take the same drugs from the FDA, and is updated regularly.

What is Fentanyl?

Fentanyl has active ingredients of fentanyl citrate. It is often used in pain. eHealthMe is studying from 73,301 Fentanyl users. Check the latest studies of Fentanyl.

What is Daliresp?

Daliresp has active ingredients of roflumilast. It is often used in chronic obstructive pulmonary disease. eHealthMe is studying from 4,722 Daliresp users. Check the latest studies of Daliresp.

On Jul, 10, 2026

28 people who take Fentanyl and Daliresp together, and have interactions are studied.

Fentanyl and Daliresp drug interactions.

What are the common drug interactions of Fentanyl and Daliresp, by gender? *:

female:

Somnolence (a state of near-sleep, a strong desire for sleep)
Abnormal behaviour
Death
Dysphagia (a condition in which swallowing is difficult or painful)
Heart rate decreased
Hypokinesia (decreased bodily movement)
Lethargy (tiredness)
Fall
Upper limb fracture
Arteriosclerosis (thickening and hardening of arteries)

male:

Death
Abdominal discomfort
Drug intolerance (drug sensitivity)
Dyspnoea (difficult or laboured respiration)
Erythema (redness of the skin)
Lung adenocarcinoma recurrent (reoccurrence of a form of non-small cell lung cancer)
Metastases to kidney (cancer spreads to kidney)
Pneumonia
Pneumonia pseudomonal (pseudomonas pneumonia is an infection caused by the microbe known as pseudomonas aeruginosa)
Productive cough

What are the common drug interactions of Fentanyl and Daliresp, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Bronchitis (inflammation of the mucous membrane in the bronchial tubes)

40-49:

n/a

50-59:

Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Vertigo
Balance disorder
Dizziness
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)

60+:

Death
Abnormal behaviour
Hypoacusis (loss of hearing)
Muscle spasms (muscle contraction)
Osteoporosis (bones weak and more likely to break)
Pneumonia
Productive cough
Hospitalisation
Abdominal discomfort
Acute respiratory failure

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 17.86%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 5 people, 17.86%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 14.29%
Breakthrough Pain: 4 people, 14.29%
Neoplasm Malignant (cancer tumour): 3 people, 10.71%
Insomnia (sleeplessness): 3 people, 10.71%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 10.71%
Hypokalemia (low potassium): 3 people, 10.71%
Dyspnea (difficult or laboured breathing): 3 people, 10.71%
Depression: 3 people, 10.71%

* Approximation only. Some reports may have incomplete information.

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