Fentanyl and Normodyne drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Fentanyl (fentanyl citrate) and Normodyne (labetalol hydrochloride). Common drug interactions include acute respiratory failure among females and compartment syndrome among males.

The phase IV clinical study analyzes what interactions people have when they take Fentanyl and Normodyne. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Fentanyl?

Fentanyl has active ingredients of fentanyl citrate. It is often used in pain. eHealthMe is studying from 73,301 Fentanyl users. Check the latest studies of Fentanyl.

What is Normodyne?

Normodyne has active ingredients of labetalol hydrochloride. eHealthMe is studying from 858 Normodyne users. Check the latest studies of Normodyne.

On Jul, 16, 2026

14 people who take Fentanyl and Normodyne together, and have interactions are studied.

Fentanyl and Normodyne drug interactions.

What are the common drug interactions of Fentanyl and Normodyne, by gender? *:

female:

Acute respiratory failure
Candida sepsis (candida in blood stream)
Hypoxia (low oxygen in tissues)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Vomiting
Abdominal distension
Blood bilirubin decreased
Blood creatinine increased
Blood glucose increased
Blood potassium increased

male:

Compartment syndrome (painful condition that occurs when pressure within the muscles builds to dangerous levels)
Hypertension (high blood pressure)
Muscle necrosis (muscle cell damage)
Oedema (fluid collection in tissue)
Rectal haemorrhage (bleeding from anus)
Renal failure acute (rapid kidney dysfunction)
Small intestinal obstruction (blockage in small intestine)
Abdominal pain upper
Anaemia (lack of blood)
Cerebral haemorrhage (bleeding within the brain)

What are the common drug interactions of Fentanyl and Normodyne, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Blood bilirubin decreased
Blood creatinine increased
Blood glucose increased
Blood potassium increased
Blood sodium decreased
Blood urea increased
Carbon dioxide decreased
Chest pain
Enterovirus test positive
Glomerular filtration rate decreased

50-59:

Feeding tube complication
Haematoma (collection of blood outside the blood vessels)
Hypertension (high blood pressure)
Muscle necrosis (muscle cell damage)
Oedema (fluid collection in tissue)
Acute respiratory failure
Candida sepsis (candida in blood stream)
Hypoxia (low oxygen in tissues)
Compartment syndrome (painful condition that occurs when pressure within the muscles builds to dangerous levels)

60+:

Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Cerebral haemorrhage (bleeding within the brain)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Intracranial pressure increased (high pressure inside the skull and thus in the brain tissue and cerebrospinal fluid)
Rectal haemorrhage (bleeding from anus)

What are the existing conditions these people have? *

High Blood Pressure: 5 people, 35.71%
Nausea (feeling of having an urge to vomit): 5 people, 35.71%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 4 people, 28.57%
Wrist Fracture: 3 people, 21.43%
Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 3 people, 21.43%
Breast Infection: 3 people, 21.43%
Constipation: 3 people, 21.43%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 3 people, 21.43%
Depression: 3 people, 21.43%
Dermatitis Contact (skin reaction (dermatitis) resulting from exposure to allergens): 3 people, 21.43%

* Approximation only. Some reports may have incomplete information.

Do you take Fentanyl and Normodyne?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously