Fentanyl and Propulsid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Fentanyl (fentanyl citrate) and Propulsid (cisapride monohydrate). Common drug interactions include infectious mononucleosis among females and abdominal pain among males.

The phase IV clinical study analyzes what interactions people have when they take Fentanyl and Propulsid. It is created by eHealthMe based on reports of 35 people who take the same drugs from the FDA, and is updated regularly.

What is Fentanyl?

Fentanyl has active ingredients of fentanyl citrate. It is often used in pain. eHealthMe is studying from 73,301 Fentanyl users. Check the latest studies of Fentanyl.

What is Propulsid?

Propulsid has active ingredients of cisapride monohydrate. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 8,130 Propulsid users. Check the latest studies of Propulsid.

On Jul, 23, 2026

35 people who take Fentanyl and Propulsid together, and have interactions are studied.

Fentanyl and Propulsid drug interactions.

What are the common drug interactions of Fentanyl and Propulsid, by gender? *:

female:

Infectious mononucleosis (infection usually caused by the epstein-barr virus)
Insomnia (sleeplessness)
Jaw disorder (jaw disease)
Leukocytosis (increased white blood cells)
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Metastases to liver (cancer spreads to liver)
Mucosal inflammation (infection of mucous membrane)
Mucosal ulceration (ulcers of mucous membrane)
Multi-organ failure (multisystem organ failure)
Necrosis (the death of body tissue)

male:

Abdominal pain
Constipation
Brain neoplasm (tumour of brain)
Conjunctivitis (pink eye)
Dermatitis exfoliative (widespread scaling of the skin, often with itching (pruritus), skin redness (erythroderma), and hair loss)
Haemoglobin decreased
Hypotension (abnormally low blood pressure)
Myoclonic jerks (involuntary twitching of a muscle or group of muscles)
Pulmonary embolism (blockage of the main artery of the lung)
Pyrexia (fever)

What are the common drug interactions of Fentanyl and Propulsid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
Dyskinesia (abnormality or impairment of voluntary movement)
Encephalitis viral (inflammation of the brain due to viral infection)
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures)
Hypertonia (abnormal increase in muscle tension and a reduced ability of a muscle to stretch)

10-19:

Drug maladministration
Electrocardiogram abnormal
Electrocardiogram qt corrected interval prolonged
Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)

20-29:

Torsade de pointes (a abnormal heart rate with abnormal beating pattern)

30-39:

Activated partial thromboplastin time prolonged
Biliary fistula
Cardiac arrest
Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
Cytomegalovirus infection
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
Dyspnoea (difficult or laboured respiration)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Grand mal convulsion (a type of generalized seizure that affects the entire brain)
Haematoma (collection of blood outside the blood vessels)

40-49:

Blood calcium increased
Blood creatinine increased
Blood potassium decreased
Blood urea decreased
Blood urea increased
Bone disorder
Carotid artery stenosis (narrowing of carotid artery)
Constipation
Dental caries
Diarrhoea

50-59:

Nausea (feeling of having an urge to vomit)
Vomiting
Abdominal pain
Constipation
Diarrhoea
Epistaxis (bleed from the nose)
Neck pain
Pain in limb
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Radiculopathy (a set of conditions in which one or more nerves is affected and does not work properly)

60+:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Multi-organ failure (multisystem organ failure)
Nausea (feeling of having an urge to vomit)
Renal failure (kidney dysfunction)
Renal impairment (severely reduced kidney function)
Renal injury (kidney injury)
Stress
Aortic stenosis (obstruction to the outflow of blood from the left ventricle into the aorta)
Arteriosclerosis (thickening and hardening of arteries)

What are the existing conditions these people have? *

Migraine (headache): 3 people, 8.57%

* Approximation only. Some reports may have incomplete information.

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