Fentanyl and Proventil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Fentanyl (fentanyl citrate) and Proventil (albuterol). Common drug interactions include peripheral swelling among females and hypotension among males.

The phase IV clinical study analyzes what interactions people have when they take Fentanyl and Proventil. It is created by eHealthMe based on reports of 99 people who take the same drugs from the FDA, and is updated regularly.

What is Fentanyl?

Fentanyl has active ingredients of fentanyl citrate. It is often used in pain. eHealthMe is studying from 73,301 Fentanyl users. Check the latest studies of Fentanyl.

What is Proventil?

Proventil has active ingredients of albuterol. It is often used in asthma. eHealthMe is studying from 16,110 Proventil users. Check the latest studies of Proventil.



On Jul, 11, 2026

99 people who take Fentanyl and Proventil together, and have interactions are studied.

Fentanyl and Proventil drug interactions.

What are the common drug interactions of Fentanyl and Proventil, by gender? *:

female:

  1. Peripheral swelling
  2. Pneumonia
  3. Urinary tract infection
  4. Headache (pain in head)
  5. Pulmonary mass
  6. Abdominal pain upper
  7. Anxiety
  8. Cellulitis (infection under the skin)
  9. Sepsis (a severe blood infection that can lead to organ failure and death)
  10. Arthralgia (joint pain)

male:

  1. Hypotension (abnormally low blood pressure)
  2. Dyspnoea (difficult or laboured respiration)
  3. Status asthmaticus (a asthma attack not responds to regular medicines)
  4. Drug intolerance (drug sensitivity)
  5. Duodenal ulcer haemorrhage (bleeding duodenal ulcer)
  6. Hepatic necrosis (large portions of liver die off due to severe liver disease)
  7. Ileus paralytic (obstruction of the intestine due to paralysis of the intestinal muscles)
  8. Peritoneal haemorrhage (peritoneal bleeding)
  9. Pulmonary haemorrhage (acute bleeding from the lung)
  10. Renal tubular necrosis (death of kidney tubules)

What are the common drug interactions of Fentanyl and Proventil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Cardiogenic shock (inadequate circulation of blood)
  2. Disseminated intravascular coagulation (systemic activation of blood coagulation)
  3. Gastrointestinal necrosis (destruction of gastrointestinal organ)
  4. Hepatic failure (liver failure)
  5. Hypotension (abnormally low blood pressure)
  6. Lactic acidosis (low ph in body tissues)
  7. Renal failure (kidney dysfunction)
  8. Respiratory failure (inadequate gas exchange by the respiratory system)
  9. Septic shock (shock due to blood infection)
  10. Status asthmaticus (a asthma attack not responds to regular medicines)

20-29:

  1. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  2. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  3. Pulmonary embolism (blockage of the main artery of the lung)

30-39:

  1. Abortion induced (medically referred abortion)
  2. Asthenia (weakness)
  3. Cellulitis staphylococcal (a type of bacteria originated skin soft tissue infection)
  4. Malaise (a feeling of general discomfort or uneasiness)
  5. Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
  6. Ataxia (loss of full control of bodily movements)
  7. Blood pressure decreased
  8. Cough
  9. Decreased appetite
  10. Depression

40-49:

  1. Dyspnoea (difficult or laboured respiration)
  2. Dysuria (painful or difficult urination)
  3. Anxiety
  4. Emotional distress
  5. Injury
  6. Leukocytosis (increased white blood cells)
  7. Oedema peripheral (superficial swelling)
  8. Road traffic accident
  9. Sepsis (a severe blood infection that can lead to organ failure and death)
  10. Tooth abscess (pus formation in tooth)

50-59:

  1. Dizziness
  2. Fall
  3. Fatigue (feeling of tiredness)
  4. Femur fracture
  5. Gait disturbance
  6. Gastrointestinal pain
  7. Haematemesis (vomiting of blood)
  8. Hypertension (high blood pressure)
  9. Hypocalcaemia (levels of calcium in blood serum are abnormally low)
  10. Hypokalaemia (low potassium)

60+:

  1. Vomiting
  2. Dyspnoea (difficult or laboured respiration)
  3. Peripheral swelling
  4. Septic shock (shock due to blood infection)
  5. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  6. Cardiac failure congestive
  7. Cardiac arrest
  8. Dysphagia (a condition in which swallowing is difficult or painful)
  9. Influenza
  10. Neuropathy peripheral (surface nerve damage)

What are the existing conditions these people have? *

  1. Nausea (feeling of having an urge to vomit): 11 people, 11.11%
  2. Depression: 10 people, 10.10%
  3. Muscle Spasms (muscle contraction): 10 people, 10.10%
  4. Constipation: 8 people, 8.08%
  5. Diabetes: 8 people, 8.08%
  6. Multiple Myeloma (cancer of the plasma cells): 8 people, 8.08%
  7. High Blood Pressure: 7 people, 7.07%
  8. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 7.07%
  9. Wheezing (a high-pitched whistling sound made while you breath): 6 people, 6.06%
  10. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 6 people, 6.06%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Fentanyl and Proventil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Fentanyl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Proventil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Fentanyl and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Proventil and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on fentanyl citrate and albuterol (the active ingredients of Fentanyl and Proventil, respectively), and Fentanyl and Proventil (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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