Fentanyl and Selenium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Fentanyl (fentanyl citrate) and Selenium (selenium). Common drug interactions include spinal osteoarthritis among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Fentanyl and Selenium. It is created by eHealthMe based on reports of 64 people who take the same drugs from the FDA, and is updated regularly.

What is Fentanyl?

Fentanyl has active ingredients of fentanyl citrate. It is often used in pain. eHealthMe is studying from 73,301 Fentanyl users. Check the latest studies of Fentanyl.

What is Selenium?

Selenium has active ingredients of selenium. It is often used in vitamin supplementation. eHealthMe is studying from 5,314 Selenium users. Check the latest studies of Selenium.



On Aug, 11, 2026

64 people who take Fentanyl and Selenium together, and have interactions are studied.

Fentanyl and Selenium drug interactions.

What are the common drug interactions of Fentanyl and Selenium, by gender? *:

female:

  1. Spinal osteoarthritis (joint cartilage loss in spine)
  2. Oedema peripheral (superficial swelling)
  3. Cardiomegaly (increased size of heart than normal)
  4. Neuropathy peripheral (surface nerve damage)
  5. Pulmonary fibrosis (formation or development of excess fibrous connective tissue (fibrosis) in the lungs)
  6. Toothache (tooth pain)
  7. Cough
  8. Neck pain
  9. Bone disorder
  10. Emotional distress

male:

  1. Anxiety
  2. Injury
  3. Abscess (pus)
  4. Allodynia (a condition in which pain is caused by a stimulus that does not normally elicit pain)
  5. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  6. Ankle fracture
  7. Aortic arteriosclerosis (hardening of the aortic arteries)
  8. Atelectasis (partial or complete collapse of the lung)
  9. Blood urea nitrogen/creatinine ratio increased
  10. Bronchopleural fistula

What are the common drug interactions of Fentanyl and Selenium, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Atelectasis (partial or complete collapse of the lung)
  2. Dehydration (dryness resulting from the removal of water)
  3. Diarrhoea
  4. Haemorrhage (bleeding)
  5. Hypotonia (low muscle tone)
  6. Respiratory failure (inadequate gas exchange by the respiratory system)
  7. Viral infection

10-19:

  1. Alanine aminotransferase increased
  2. Aspartate aminotransferase increased
  3. Blood selenium increased
  4. Fatigue (feeling of tiredness)
  5. Headache (pain in head)
  6. Oral herpes (viral infection of mouth)
  7. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  8. Partial seizures (seizures which affect only a part of the brain at onset)
  9. Bacterial infection
  10. Fluid intake reduced

20-29:

n/a

30-39:

n/a

40-49:

  1. Hypovolaemic shock (shock caused by severe blood or fluid loss)
  2. Lower gastrointestinal haemorrhage (bleeding in the large intestine, rectum, or anus is called lower gi bleeding)
  3. Abscess limb (limb infection)
  4. Anal abscess
  5. Cellulitis (infection under the skin)
  6. Cellulitis of male external genital organ (infection of male genitals soft tissue)
  7. Cellulitis staphylococcal (a type of bacteria originated skin soft tissue infection)
  8. Emotional distress
  9. Gangrene (body tissue dies)
  10. Genital abscess (build up of pus in genital)

50-59:

  1. Spinal osteoarthritis (joint cartilage loss in spine)
  2. Cardiomegaly (increased size of heart than normal)
  3. Neuropathy peripheral (surface nerve damage)
  4. Pulmonary fibrosis (formation or development of excess fibrous connective tissue (fibrosis) in the lungs)
  5. Toothache (tooth pain)
  6. Cough
  7. Neck pain
  8. Injury
  9. Emotional distress
  10. Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs)

60+:

  1. Cellulitis (infection under the skin)
  2. Disease progression
  3. Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
  4. Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
  5. Prostate cancer metastatic
  6. Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)
  7. Respiratory failure (inadequate gas exchange by the respiratory system)
  8. Septic shock (shock due to blood infection)
  9. Unresponsive to stimuli
  10. Arteriovenous graft site infection

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 14 people, 21.88%
  2. Bone Density Abnormal: 9 people, 14.06%
  3. Osteoporosis (bones weak and more likely to break): 5 people, 7.81%
  4. Metastases To Bone (cancer spreads to bone): 5 people, 7.81%
  5. Breast Cancer: 5 people, 7.81%
  6. Bone Cancer Metastatic: 5 people, 7.81%
  7. Stress And Anxiety: 4 people, 6.25%
  8. Prostate Cancer Metastatic: 4 people, 6.25%
  9. Osteomyelitis (infection of bone): 4 people, 6.25%
  10. Constipation: 4 people, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Fentanyl and Selenium?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Fentanyl and Selenium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Fentanyl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Selenium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Fentanyl and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Selenium and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on fentanyl citrate and selenium (the active ingredients of Fentanyl and Selenium, respectively), and Fentanyl and Selenium (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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