Fentanyl and Tasigna drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Fentanyl (fentanyl citrate) and Tasigna (nilotinib hydrochloride monohydrate). Common drug interactions include hypoaesthesia among females and nausea among males.

The phase IV clinical study analyzes what interactions people have when they take Fentanyl and Tasigna. It is created by eHealthMe based on reports of 49 people who take the same drugs from the FDA, and is updated regularly.

What is Fentanyl?

Fentanyl has active ingredients of fentanyl citrate. It is often used in pain. eHealthMe is studying from 73,301 Fentanyl users. Check the latest studies of Fentanyl.

What is Tasigna?

Tasigna has active ingredients of nilotinib hydrochloride monohydrate. It is often used in chronic myelogenous leukemia (cml). eHealthMe is studying from 31,535 Tasigna users. Check the latest studies of Tasigna.

On Jul, 14, 2026

49 people who take Fentanyl and Tasigna together, and have interactions are studied.

What are the common drug interactions of Fentanyl and Tasigna, by gender? *:

female:

Hypoaesthesia (reduced sense of touch or sensation)
Laceration (tearing of soft body tissue)
Loss of consciousness
Lung disorder (lung disease)
Migraine (headache)
Nasal oedema (fluid collection in nose)
Oral mucosal blistering (mouth ulcer)
Palpitations (feelings or sensations that your heart is pounding or racing)
Photophobia (extreme sensitivity to light)
Pollakiuria (abnormally frequent passage of relatively small quantities or urine)

male:

Nausea (feeling of having an urge to vomit)
Headache (pain in head)
Chronic lymphocytic leukaemia transformation (white blood cell cancer changes in fast growing cancer in lymph node)
Diarrhoea
Dyspnoea (difficult or laboured respiration)
Dyspnoea paroxysmal nocturnal (respiratory distress that awakens patients from sleep)
Failure to thrive (inadequate weight gain and physical growth in children)
Fluid retention (an abnormal accumulation of fluid in the blood)
Frustration (a form of poorly expressed anger)
Hallucination (an experience involving the perception of something not present)

What are the common drug interactions of Fentanyl and Tasigna, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Abdominal pain upper
Diarrhoea
Nausea (feeling of having an urge to vomit)
Pancreatitis acute (sudden inflammation of pancreas)
Vomiting
Acute graft versus host disease (acute complication following an allogeneic tissue/blood transplant)
Alanine aminotransferase increased
Aspartate aminotransferase increased
Constipation
Drug ineffective

20-29:

Blood bilirubin increased

30-39:

Leukaemic infiltration (change in leukaemia in which leukemic cells permeate various organs at any stage of the disease)
Rash

40-49:

Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Generalised oedema (swelling all over the body)
Hepatic failure (liver failure)
Hunger
Hyperhidrosis (abnormally increased sweating)
Hypoaesthesia (reduced sense of touch or sensation)
Laceration (tearing of soft body tissue)
Lactose intolerance (inability to digest lactose)
Lethargy (tiredness)
Loss of consciousness

50-59:

Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Pneumonia
Pyrexia (fever)
Rash
Acne (skin problems that cause pimples)
Onychoclasis (breaking of the nails)
Skin exfoliation (removal of the oldest dead skin cells)
Trichorrhexis (a condition in which the hairs break)
Alopecia (absence of hair from areas of the body)
Muscular weakness (muscle weakness)

60+:

Arthralgia (joint pain)
Headache (pain in head)
Dyspnoea paroxysmal nocturnal (respiratory distress that awakens patients from sleep)
Failure to thrive (inadequate weight gain and physical growth in children)
Fluid retention (an abnormal accumulation of fluid in the blood)
Frustration (a form of poorly expressed anger)
Hallucination (an experience involving the perception of something not present)
Hypertension (high blood pressure)
Leukaemic infiltration (change in leukaemia in which leukemic cells permeate various organs at any stage of the disease)
Marrow hyperplasia (increased bone marrow)

What are the existing conditions these people have? *

Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 37 people, 75.51%
Joint Pain: 7 people, 14.29%
High Blood Pressure: 5 people, 10.20%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 4 people, 8.16%
Nausea (feeling of having an urge to vomit): 3 people, 6.12%
Itching: 3 people, 6.12%
Insomnia (sleeplessness): 3 people, 6.12%
Gastrointestinal Stromal Tumor: 3 people, 6.12%

* Approximation only. Some reports may have incomplete information.

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