Fetzima and Morphine sulfate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Fetzima (levomilnacipran hydrochloride) and Morphine sulfate (morphine sulfate). Common drug interactions include bedridden among females and acne among males.

The phase IV clinical study analyzes what interactions people have when they take Fetzima and Morphine sulfate. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Fetzima?

Fetzima has active ingredients of levomilnacipran hydrochloride. It is often used in depression. eHealthMe is studying from 2,077 Fetzima users. Check the latest studies of Fetzima.

What is Morphine sulfate?

Morphine sulfate has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 87,261 Morphine sulfate users. Check the latest studies of Morphine sulfate.



On Jul, 12, 2026

23 people who take Fetzima and Morphine sulfate together, and have interactions are studied.

Fetzima and Morphine sulfate drug interactions.

What are the common drug interactions of Fetzima and Morphine Sulfate, by gender? *:

female:

  1. Bedridden
  2. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  3. Accident
  4. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  5. Blood glucose decreased
  6. Brain injury
  7. Drug hypersensitivity
  8. Hypotension (abnormally low blood pressure)
  9. Lower limb fracture
  10. Memory impairment

male:

  1. Acne (skin problems that cause pimples)
  2. Chest pain
  3. Multiple allergies (allergy to multiple agents)
  4. Pancreatitis (inflammation of pancreas)
  5. Dehydration (dryness resulting from the removal of water)
  6. Fatigue (feeling of tiredness)
  7. Flatulence (flatus expelled through the anus)
  8. Intestinal obstruction
  9. Decreased appetite
  10. Swelling

What are the common drug interactions of Fetzima and Morphine Sulfate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Bedridden
  2. Memory impairment

30-39:

  1. Accident
  2. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  3. Blood glucose decreased
  4. Brain injury
  5. Hypotension (abnormally low blood pressure)
  6. Lower limb fracture
  7. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  8. Sensory loss (senses loss)
  9. Spinal fracture (fracture in one of vertebrae)
  10. Upper limb fracture

40-49:

n/a

50-59:

  1. Drug hypersensitivity
  2. Dehydration (dryness resulting from the removal of water)
  3. Fatigue (feeling of tiredness)
  4. Flatulence (flatus expelled through the anus)
  5. Intestinal obstruction

60+:

  1. Acne (skin problems that cause pimples)
  2. Chest pain
  3. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  4. Death
  5. Decreased appetite
  6. Increased appetite
  7. Multiple allergies (allergy to multiple agents)
  8. Swelling
  9. Weight increased
  10. Neuropathy peripheral (surface nerve damage)

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 6 people, 26.09%
  2. Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 4 people, 17.39%
  3. Malabsorption (a state arising from abnormality in absorption of food nutrients across the gastrointestinal (gi) tract): 4 people, 17.39%
  4. Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 4 people, 17.39%
  5. Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 4 people, 17.39%
  6. Multiple Myeloma (cancer of the plasma cells): 3 people, 13.04%
  7. Mental Disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 3 people, 13.04%
  8. Generalized Anxiety Disorder (excessive, uncontrollable, unexplained and often irrational worry): 3 people, 13.04%
  9. Arthritis (form of joint disorder that involves inflammation of one or more joints): 3 people, 13.04%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Fetzima and Morphine sulfate:

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Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Fetzima:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Morphine sulfate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Fetzima and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Morphine sulfate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on levomilnacipran hydrochloride and morphine sulfate (the active ingredients of Fetzima and Morphine sulfate, respectively), and Fetzima and Morphine sulfate (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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