Filspari and Jardiance drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Filspari (sparsentan) and Jardiance (empagliflozin). Common drug interactions include migraine among females and dizziness among males.

The phase IV clinical study analyzes what interactions people have when they take Filspari and Jardiance. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Filspari?

Filspari has active ingredients of sparsentan. eHealthMe is studying from 1,185 Filspari users. Check the latest studies of Filspari.

What is Jardiance?

Jardiance has active ingredients of empagliflozin. It is often used in hyperglycemia. eHealthMe is studying from 44,460 Jardiance users. Check the latest studies of Jardiance.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

16 people who take Filspari and Jardiance together, and have interactions are studied.

Filspari and Jardiance drug interactions.

What are the common drug interactions of Filspari and Jardiance, by gender? *:

female:

Migraine (headache)
Fatigue (feeling of tiredness)
Decreased appetite
Headache (pain in head)
Nervousness
Poor quality sleep
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
Glomerular filtration rate decreased
Protein total increased
Dizziness

male:

Dizziness
Fatigue (feeling of tiredness)
Contusion (a type of hematoma of tissue in which capillaries)
Diarrhoea
Dry mouth
Dyspepsia (indigestion)
Dyspnoea (difficult or laboured respiration)
Ear infection
Headache (pain in head)
Influenza

What are the common drug interactions of Filspari and Jardiance, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Fatigue (feeling of tiredness)
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
Glomerular filtration rate decreased
Migraine (headache)
Protein total increased
Blood pressure increased
Chills (felling of cold)
Diarrhoea
Dizziness
Dry mouth

30-39:

Decreased appetite
Headache (pain in head)
Nervousness
Poor quality sleep
Fatigue (feeling of tiredness)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Migraine (headache)
Tremor (trembling or shaking movements in one or more parts of your body)
Chest discomfort
Dyspnoea (difficult or laboured respiration)

40-49:

Dizziness
Multiple allergies (allergy to multiple agents)
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Orthostatic hypertension (a medical condition consisting of a sudden increase in blood pressure when a person stands up)
Contusion (a type of hematoma of tissue in which capillaries)
Pharyngitis streptococcal (inflammation of the pharynx caused by infection from. streptococcus)
Muscle spasms (muscle contraction)

50-59:

Anxiety
Dizziness
Influenza

60+:

n/a

What are the existing conditions these people have? *

Iga Nephropathy (kidney disease- condition prevents the kidneys from filtering waste): 14 people, 87.50%
Chronic Kidney Disease: 4 people, 25.00%
Haematuria (presence of blood in urine): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

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