Fintepla and Keppra xr drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Fintepla (fenfluramine hydrochloride) and Keppra xr (levetiracetam). Common drug interactions include hypersomnia among females and somnolence among males.
The phase IV clinical study analyzes what interactions people have when they take Fintepla and Keppra xr. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.
What is Fintepla?
Fintepla has active ingredients of fenfluramine hydrochloride. eHealthMe is studying from 2,613 Fintepla users. Check the latest studies of Fintepla.
What is Keppra xr?
Keppra xr has active ingredients of levetiracetam. It is often used in epilepsy. eHealthMe is studying from 2,272 Keppra xr users. Check the latest studies of Keppra xr.
12 people who take Fintepla and Keppra xr together, and have interactions are studied.

What are the common drug interactions of Fintepla and Keppra Xr, by gender? *:
female:
- Hypersomnia (excessive daytime sleepiness (eds))
- Pericardial effusion (fluid around the heart)
- Schizophrenia (a mental disorder characterized by a breakdown of thought processes)
- Screaming (a long loud piercing cry)
- Seizure cluster (small group of seizure)
- Urinary retention (the inability to completely or partially empty the bladder)
- Blood pressure decreased
- Weight increased
- Drug ineffective
- Anger
male:
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Decreased appetite
- Fatigue (feeling of tiredness)
- Seizure cluster (small group of seizure)
- Weight decreased
What are the common drug interactions of Fintepla and Keppra Xr, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
- Decreased appetite
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Drug ineffective
20-29:
- Weight decreased
30-39:
- Anger
- Back pain
- Urinary retention (the inability to completely or partially empty the bladder)
- Blood pressure decreased
- Weight increased
- Diarrhoea
- Dry skin
- Hallucination, auditory (perceiving sounds without auditory stimulus)
- Hypersomnia (excessive daytime sleepiness (eds))
- Pericardial effusion (fluid around the heart)
40-49:
n/a
50-59:
n/a
60+:
n/a
What are the existing conditions these people have? *
- Lennox-Gastaut Syndrome (epilepsy characterized by frequent seizures and different seizure types): 7 people, 58.33%
- Seizures (abnormal excessive or synchronous neuronal activity in the brain): 4 people, 33.33%
- Idiopathic Generalised Epilepsy (epileptic disorders that are believed to have a strong underlying genetic basis): 2 people, 16.67%
* Approximation only. Some reports may have incomplete information.
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Fintepla and Keppra xr:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Fintepla:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Keppra xr:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Fintepla and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Keppra xr and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Schattner A, Al-Bewerat A, "Levetiracetam (Keppra), urinary retention and literature search", A fatty cause of renal failure; what is your diagnosis?, 2016 Oct .
- Spengler DC, Montouris GD, Hohler AD, "Levetiracetam as a possible contributor to acute kidney injury", Clinical therapeutics, 2014 Aug .
- Almeida DM, Jean MR, Chystsiakova A, Monahan E, Oliveira SB, Monteiro IM, "Levetiracetam-associated acute pancreatitis in an adolescent with autism: a case report", Pancreas, 2013 Jan .
- Schattner A, Al-Bewerat A, "Levetiracetam (Keppra), urinary retention and literature search", A fatty cause of renal failure; what is your diagnosis?, 2016 Oct .
- Spengler DC, Montouris GD, Hohler AD, "Levetiracetam as a possible contributor to acute kidney injury", Clinical therapeutics, 2014 Aug .
- Almeida DM, Jean MR, Chystsiakova A, Monahan E, Oliveira SB, Monteiro IM, "Levetiracetam-associated acute pancreatitis in an adolescent with autism: a case report", Pancreas, 2013 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on fenfluramine hydrochloride and levetiracetam (the active ingredients of Fintepla and Keppra xr, respectively), and Fintepla and Keppra xr (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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