Fioricet and Accupril drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Fioricet (acetaminophen; butalbital; caffeine) and Accupril (quinapril hydrochloride). Common drug interactions include depression among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Fioricet and Accupril. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Fioricet?

Fioricet has active ingredients of acetaminophen; butalbital; caffeine. It is often used in migraine. eHealthMe is studying from 12,423 Fioricet users. Check the latest studies of Fioricet.

What is Accupril?

Accupril has active ingredients of quinapril hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 13,404 Accupril users. Check the latest studies of Accupril.

On Jul, 19, 2026

23 people who take Fioricet and Accupril together, and have interactions are studied.

Fioricet and Accupril drug interactions.

What are the common drug interactions of Fioricet and Accupril, by gender? *:

female:

Depression
Drug ineffective
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Suicidal ideation
Suicide attempt
Vomiting
Malaise (a feeling of general discomfort or uneasiness)
Chest pain
Dehydration (dryness resulting from the removal of water)
Diarrhoea

male:

Anxiety
Ataxia (loss of full control of bodily movements)
Drug maladministration
Dysarthria (speech disorder)
Encephalopathy (functioning of the brain is affected by some agent or condition)
Myositis (inflammation of the muscles)
Postural hypotension
Renal cancer (cancer of kidney)
Renal failure acute (rapid kidney dysfunction)
Upper limb fracture

What are the common drug interactions of Fioricet and Accupril, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Chest pain
Vasodilatation (widening of blood vessels resulting from relaxation of smooth muscle cells within the vessel walls)
Vomiting
Drug dependence
Malaise (a feeling of general discomfort or uneasiness)
Nausea (feeling of having an urge to vomit)

40-49:

Albumin globulin ratio decreased
Anaemia of chronic disease
Asthenia (weakness)
Bacteria urine identified
Balance disorder
Blood albumin decreased
Blood alkaline phosphatase increased
Blood chloride decreased
Blood culture positive
Blood erythropoietin increased

50-59:

Arthralgia (joint pain)
Diarrhoea
Nausea (feeling of having an urge to vomit)
Pain
Abdominal pain upper
Angioneurotic oedema (swelling that occurs just beneath the surface of the skin or mucous membranes)
Anxiety
Aphonia (inability to produce voice)
Asthma
Ataxia (loss of full control of bodily movements)

60+:

Anxiety
Blood potassium decreased
Back injury
Bipolar disorder (mood disorder)
Blepharospasm (any abnormal contraction or twitch of the eyelid)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Depression
Diarrhoea
Drug ineffective
Dry mouth

What are the existing conditions these people have? *

Depression: 8 people, 34.78%
Insomnia (sleeplessness): 6 people, 26.09%
Headache (pain in head): 3 people, 13.04%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 13.04%
Stress And Anxiety: 2 people, 8.70%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 8.70%
Psoriasis (immune-mediated disease that affects the skin): 2 people, 8.70%
Pain: 2 people, 8.70%
Osteoporosis (bones weak and more likely to break): 2 people, 8.70%
Nausea (feeling of having an urge to vomit): 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

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