Fioricet and Antivert drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Fioricet (acetaminophen; butalbital; caffeine) and Antivert (meclizine hydrochloride). Common drug interactions include heart rate decreased among females and drug ineffective among males.

The phase IV clinical study analyzes what interactions people have when they take Fioricet and Antivert. It is created by eHealthMe based on reports of 49 people who take the same drugs from the FDA, and is updated regularly.

What is Fioricet?

Fioricet has active ingredients of acetaminophen; butalbital; caffeine. It is often used in migraine. eHealthMe is studying from 12,423 Fioricet users. Check the latest studies of Fioricet.

What is Antivert?

Antivert has active ingredients of meclizine hydrochloride. It is often used in dizziness. eHealthMe is studying from 4,087 Antivert users. Check the latest studies of Antivert.

On Jul, 17, 2026

49 people who take Fioricet and Antivert together, and have interactions are studied.

Fioricet and Antivert drug interactions.

What are the common drug interactions of Fioricet and Antivert, by gender? *:

female:

Heart rate decreased
Hypersomnia (excessive daytime sleepiness (eds))
Hypertension (high blood pressure)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Impetigo (contagious skin infection)
Nausea (feeling of having an urge to vomit)
Blood pressure increased
Mood swings (an extreme or rapid change in mood)
Agitation (state of anxiety or nervous excitement)
Anger

male:

Drug ineffective
Anxiety
Injection site mass
Metabolic syndrome (a combination of the medical disorders that, when occurring together, increase the risk of developing cardiovascular disease)
Mood altered (changes in mood)
Overdose
Prostate cancer
Respiratory tract congestion (blockage on respiratory system)
Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
Sleep disorder

What are the common drug interactions of Fioricet and Antivert, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Subdural haematoma (blood collects between the skull and the surface of the brain)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diabetic gastropathy (gastric neuromuscular dysfunction in diabetes mellitus)
Difficulty in walking
Drug effect decreased
Hypoaesthesia (reduced sense of touch or sensation)
Injection site erythema (redness at injection site)
Injection site mass

40-49:

Chronic kidney disease
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Emotional distress
Hallucination, auditory (perceiving sounds without auditory stimulus)
Pain
Psychotic disorder

50-59:

Blood pressure increased
Nausea (feeling of having an urge to vomit)
Arthralgia (joint pain)
Suicidal ideation
Agitation (state of anxiety or nervous excitement)
Anger
Application site erythema (redness of the skin at application site)
Application site pruritus (application site severe itching of the skin)
Asthenia (weakness)
Back pain

60+:

Anxiety
Dehydration (dryness resulting from the removal of water)
Asthenia (weakness)
Asthma
Atrioventricular block first degree (heart block first degree)
Back injury
Bipolar disorder (mood disorder)
Blepharospasm (any abnormal contraction or twitch of the eyelid)
Blood pressure systolic increased
Calcinosis (calcium deposits in any soft tissue)

What are the existing conditions these people have? *

Headache (pain in head): 13 people, 26.53%
Nausea (feeling of having an urge to vomit): 8 people, 16.33%
Constipation: 6 people, 12.24%
Muscle Spasms (muscle contraction): 6 people, 12.24%
Insomnia (sleeplessness): 6 people, 12.24%
High Blood Pressure: 5 people, 10.20%
Hypersensitivity: 4 people, 8.16%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 8.16%
High Blood Cholesterol: 4 people, 8.16%
Tardive Dyskinesia (a disorder that involves involuntary movements): 4 people, 8.16%

* Approximation only. Some reports may have incomplete information.

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