Fioricet and Tivicay drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Fioricet (acetaminophen; butalbital; caffeine) and Tivicay (dolutegravir sodium). Common drug interactions include anhedonia among females and anhedonia among males.

The phase IV clinical study analyzes what interactions people have when they take Fioricet and Tivicay. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Fioricet?

Fioricet has active ingredients of acetaminophen; butalbital; caffeine. It is often used in migraine. eHealthMe is studying from 12,423 Fioricet users. Check the latest studies of Fioricet.

What is Tivicay?

Tivicay has active ingredients of dolutegravir sodium. It is often used in hiv infection. eHealthMe is studying from 9,674 Tivicay users. Check the latest studies of Tivicay.

On Jul, 20, 2026

18 people who take Fioricet and Tivicay together, and have interactions are studied.

What are the common drug interactions of Fioricet and Tivicay, by gender? *:

female:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Emotional distress
Pain
Respiration (transport of oxygen from the outside air to the cells within tissues)
Surgery
Vestibular disorder (disorders of the body's balance (vestibular) system in the inner ear)
Asthma
Bipolar disorder (mood disorder)
Bone pain

male:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Renal failure (kidney dysfunction)
Rotator cuff repair
Spinal cord injury
Upper limb fracture
Aortic aneurysm (enlargement of an aortic artery caused by a weakening of the artery wall)
Arteriovenous malformation
Depression
Fracture

What are the common drug interactions of Fioricet and Tivicay, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Respiration (transport of oxygen from the outside air to the cells within tissues)
Surgery
Vestibular disorder (disorders of the body's balance (vestibular) system in the inner ear)
Asthma
Bipolar disorder (mood disorder)

30-39:

n/a

40-49:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Bone density decreased
Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
Chronic kidney disease
Emotional distress
Hip arthroplasty
Osteopenia (a condition where bone mineral density is lower than normal)
Osteoporosis (bones weak and more likely to break)
Pain

50-59:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Quality of life decreased
Renal failure (kidney dysfunction)
Emotional distress
Pain
Osteopenia (a condition where bone mineral density is lower than normal)
Chronic kidney disease
Depression
Fatigue (feeling of tiredness)

60+:

n/a

What are the existing conditions these people have? *

Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 16.67%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 16.67%
Urinary Retention (the inability to completely or partially empty the bladder): 2 people, 11.11%
Tension Headache: 2 people, 11.11%
Bacterial Infection: 2 people, 11.11%
Cough: 2 people, 11.11%
Depression: 2 people, 11.11%
Fungal Infection: 2 people, 11.11%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 11.11%
High Blood Pressure: 2 people, 11.11%

* Approximation only. Some reports may have incomplete information.

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