Fish oil and Optimark drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Fish oil (fish oil) and Optimark (gadoversetamide). Common drug interactions include joint contracture among females and nephrogenic systemic fibrosis among males.

The phase IV clinical study analyzes what interactions people have when they take Fish oil and Optimark. It is created by eHealthMe based on reports of 33 people who take the same drugs from the FDA, and is updated regularly.

What is Fish oil?

Fish oil has active ingredients of fish oil. It is often used in high blood cholesterol. eHealthMe is studying from 112,933 Fish oil users. Check the latest studies of Fish oil.

What is Optimark?

Optimark has active ingredients of gadoversetamide. eHealthMe is studying from 3,055 Optimark users. Check the latest studies of Optimark.



On Jul, 19, 2026

33 people who take Fish oil and Optimark together, and have interactions are studied.

Fish oil and Optimark drug interactions.

What are the common drug interactions of Fish Oil and Optimark, by gender? *:

female:

  1. Joint contracture (a permanent shortening of a muscle or joint)
  2. Joint stiffness
  3. Multi-organ failure (multisystem organ failure)
  4. Scar
  5. Skin exfoliation (removal of the oldest dead skin cells)
  6. Skin fibrosis (fibrous tissue formation on skin)
  7. Skin hyperpigmentation (disorders affect the colour of your skin)
  8. Skin induration (an abnormally hard spot or area on the skin)
  9. Neuralgia (pain in one or more nerves)
  10. Muscular weakness (muscle weakness)

male:

  1. Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
  2. Pruritus (severe itching of the skin)
  3. Anxiety
  4. Arthralgia (joint pain)
  5. Back pain
  6. Emotional distress
  7. Fatigue (feeling of tiredness)
  8. General physical health deterioration (weak health status)
  9. Joint swelling
  10. Skin induration (an abnormally hard spot or area on the skin)

What are the common drug interactions of Fish Oil and Optimark, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Abdominal pain lower
  2. Bone pain
  3. Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
  4. Joint contracture (a permanent shortening of a muscle or joint)
  5. Muscle spasms (muscle contraction)
  6. Muscle twitching
  7. Pain
  8. Renal pain (kidney pain)
  9. Skin tightness
  10. Visual impairment

40-49:

  1. Catheter related infection
  2. Catheter sepsis (bacterial infection in blood due to catheter)
  3. Dyspnoea (difficult or laboured respiration)
  4. Fluid overload (too much fluid in the blood)
  5. Injury
  6. Large intestine perforation (hole in large intestine)
  7. Pain in extremity
  8. Peritoneal infection
  9. Peritonitis bacterial (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs by bacterial)
  10. Respiratory distress (difficulty in breathing)

50-59:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Arthralgia (joint pain)
  4. Azotaemia (excess of urea or other nitrogenous compounds in the blood)
  5. Back pain
  6. Balance disorder
  7. Emotional distress
  8. Fatigue (feeling of tiredness)
  9. Fibrosis (formation of excess fibrous connective tissue in an organ or tissue)
  10. Gait disturbance

60+:

  1. Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
  2. Skin tightness
  3. Myalgia (muscle pain)
  4. Swelling
  5. Joint range of motion decreased (disease of joint movement)
  6. Stasis dermatitis (skin inflammation caused by blood pooling in the veins in your legs)
  7. Mobility decreased (ability to move is reduced)
  8. Muscular weakness (muscle weakness)
  9. Anxiety
  10. Arthralgia (joint pain)

What are the existing conditions these people have? *

  1. Pain: 7 people, 21.21%
  2. Hyperparathyroidism Secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary): 7 people, 21.21%
  3. Blood Phosphorus Increased: 7 people, 21.21%
  4. Nuclear Magnetic Resonance Imaging Brain: 6 people, 18.18%
  5. Nuclear Magnetic Resonance Imaging Abdominal: 5 people, 15.15%

* Approximation only. Some reports may have incomplete information.

Do you take Fish oil and Optimark?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Fish oil and Optimark:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Fish oil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Optimark:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Fish oil and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Optimark and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on fish oil and gadoversetamide (the active ingredients of Fish oil and Optimark, respectively), and Fish oil and Optimark (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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