Flagyl and Clindamycin phosphate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Flagyl (metronidazole) and Clindamycin phosphate (clindamycin phosphate). Common drug interactions include dizziness among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Flagyl and Clindamycin phosphate. It is created by eHealthMe based on reports of 36 people who take the same drugs from the FDA, and is updated regularly.

What is Flagyl?

Flagyl has active ingredients of metronidazole. It is often used in vaginitis bacterial. eHealthMe is studying from 25,897 Flagyl users. Check the latest studies of Flagyl.

What is Clindamycin phosphate?

Clindamycin phosphate has active ingredients of clindamycin phosphate. It is often used in infection. eHealthMe is studying from 4,216 Clindamycin phosphate users. Check the latest studies of Clindamycin phosphate.



On Jul, 05, 2026

36 people who take Flagyl and Clindamycin phosphate together, and have interactions are studied.

Flagyl and Clindamycin phosphate drug interactions.

What are the common drug interactions of Flagyl and Clindamycin Phosphate, by gender? *:

female:

  1. Dizziness
  2. Nausea (feeling of having an urge to vomit)
  3. Arthralgia (joint pain)
  4. Gait disturbance
  5. Asthenia (weakness)
  6. Fatigue (feeling of tiredness)
  7. Oesophagitis (inflammation of oesophagus)
  8. Gastrointestinal disorder (functional problems of gastrointestinal tract)
  9. Joint swelling
  10. Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)

male:

  1. Pneumonia
  2. Septic shock (shock due to blood infection)
  3. Multi-organ failure (multisystem organ failure)
  4. Vasculitis necrotising (inflammation and damage to blood vessels)
  5. Cerebral haemorrhage (bleeding within the brain)
  6. Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
  7. International normalised ratio increased
  8. Rash maculo-papular (red area on the skin that is covered with small confluent bumps)

What are the common drug interactions of Flagyl and Clindamycin Phosphate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
  2. Rash maculo-papular (red area on the skin that is covered with small confluent bumps)

20-29:

n/a

30-39:

n/a

40-49:

  1. Disturbance in attention
  2. Hyperaesthesia
  3. Hyperthyroidism (over activity of the thyroid gland)
  4. Myalgia (muscle pain)

50-59:

  1. Drug hypersensitivity
  2. Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)

60+:

  1. Drug hypersensitivity
  2. Nausea (feeling of having an urge to vomit)
  3. Vasculitis necrotising (inflammation and damage to blood vessels)
  4. Abdominal pain
  5. Cerebral haemorrhage (bleeding within the brain)
  6. Delirium (wild excitement)
  7. Eating disorder
  8. International normalised ratio increased
  9. Pruritus (severe itching of the skin)
  10. Urticaria (rash of round, red welts on the skin that itch intensely)

What are the existing conditions these people have? *

  1. Pain: 9 people, 25.00%
  2. Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 6 people, 16.67%
  3. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 6 people, 16.67%
  4. Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall): 6 people, 16.67%

* Approximation only. Some reports may have incomplete information.

Do you take Flagyl and Clindamycin phosphate?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Flagyl and Clindamycin phosphate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Flagyl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Clindamycin phosphate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Flagyl and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Clindamycin phosphate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on metronidazole and clindamycin phosphate (the active ingredients of Flagyl and Clindamycin phosphate, respectively), and Flagyl and Clindamycin phosphate (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: