Flagyl and Famvir drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Flagyl (metronidazole) and Famvir (famciclovir). Common drug interactions include swelling among females and hypotension among males.
The phase IV clinical study analyzes what interactions people have when they take Flagyl and Famvir. It is created by eHealthMe based on reports of 61 people who take the same drugs from the FDA, and is updated regularly.
What is Flagyl?
Flagyl has active ingredients of metronidazole. It is often used in vaginitis bacterial. eHealthMe is studying from 25,897 Flagyl users. Check the latest studies of Flagyl.
What is Famvir?
Famvir has active ingredients of famciclovir. It is often used in herpes labialis (oral herpes simplex). eHealthMe is studying from 3,061 Famvir users. Check the latest studies of Famvir.
61 people who take Flagyl and Famvir together, and have interactions are studied.

What are the common drug interactions of Flagyl and Famvir, by gender? *:
female:
- Swelling
- Tricuspid valve incompetence (inefficient heart valve)
- Osteopenia (a condition where bone mineral density is lower than normal)
- Exostosis (formation of new bone on the surface of a bone)
- Osteonecrosis of jaw (death of bone of jaw)
- Osteoporosis (bones weak and more likely to break)
- Anaemia (lack of blood)
- Dysphagia (a condition in which swallowing is difficult or painful)
- Fatigue (feeling of tiredness)
- Humerus fracture (injury to the upper arm bone)
male:
- Hypotension (abnormally low blood pressure)
- Hypoxia (low oxygen in tissues)
- Renal failure acute (rapid kidney dysfunction)
- Cerebral ischaemia (insufficient blood flow to the brain to meet metabolic demand)
- Cholecystitis acute (rapid infection of gallbladder)
- Febrile neutropenia (fever with reduced white blood cells)
- Respiratory distress (difficulty in breathing)
- Enterococcal bacteraemia (presence of bacteria lactic acid in the blood)
- Abdominal hernia
- Abdominal pain
What are the common drug interactions of Flagyl and Famvir, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Coagulopathy (blood's ability to clot is impaired)
- Hepatocellular injury (liver injury)
- Rash
- Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
- Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)
- Myalgia (muscle pain)
- Cytarabine syndrome (due to high dose of cytarbine consists of fever, muscle ache, bone pain, occasional chest pain, rash)
- Aphasia (damage to the parts of the brain that control language)
- Apraxia (disorder that affects a person's ability to organize the movements of the muscles used in speech)
- Blood creatine phosphokinase increased
40-49:
n/a
50-59:
- Osteopenia (a condition where bone mineral density is lower than normal)
- Pain
- Sinusitis (inflammation of sinus)
- Swelling
- Tricuspid valve incompetence (inefficient heart valve)
- Humerus fracture (injury to the upper arm bone)
- Exostosis (formation of new bone on the surface of a bone)
- Osteonecrosis of jaw (death of bone of jaw)
- Anaemia (lack of blood)
- Dysphagia (a condition in which swallowing is difficult or painful)
60+:
- Anxiety
- Cardiac failure congestive
- Injury
- Neck pain
- Renal cyst (kidney cyst)
- Sinusitis (inflammation of sinus)
- Tricuspid valve incompetence (inefficient heart valve)
- Adenoma benign (non-cancerous tumour -secreting)
- Amblyopia (lazy eye)
- Anal candidiasis (rectal fungal infection)
What are the existing conditions these people have? *
- Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 20 people, 32.79%
- Pain: 20 people, 32.79%
- Osteoporosis (bones weak and more likely to break): 20 people, 32.79%
- Multiple Myeloma (cancer of the plasma cells): 15 people, 24.59%
- Upper Respiratory Tract Infection: 12 people, 19.67%
- Restless Leg Syndrome (a powerful urge to move your legs): 12 people, 19.67%
- Muscle Spasms (muscle contraction): 12 people, 19.67%
- Bone Lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries): 12 people, 19.67%
- Thrombocytopenia (decrease of platelets in blood): 11 people, 18.03%
- Fever: 11 people, 18.03%
* Approximation only. Some reports may have incomplete information.
Do you take Flagyl and Famvir?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Flagyl and Famvir:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Flagyl:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Famvir:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Flagyl and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Famvir and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on metronidazole and famciclovir (the active ingredients of Flagyl and Famvir, respectively), and Flagyl and Famvir (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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