Flagyl and Ketamine hcl drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Flagyl (metronidazole) and Ketamine hcl (ketamine hydrochloride). Common drug interactions include pneumonia among females and deep vein thrombosis among males.

The phase IV clinical study analyzes what interactions people have when they take Flagyl and Ketamine hcl. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Flagyl?

Flagyl has active ingredients of metronidazole. It is often used in vaginitis bacterial. eHealthMe is studying from 25,897 Flagyl users. Check the latest studies of Flagyl.

What is Ketamine hcl?

Ketamine hcl has active ingredients of ketamine hydrochloride. It is often used in pain. eHealthMe is studying from 1,851 Ketamine hcl users. Check the latest studies of Ketamine hcl.



On Jul, 12, 2026

11 people who take Flagyl and Ketamine hcl together, and have interactions are studied.

Flagyl and Ketamine hcl drug interactions.

What are the common drug interactions of Flagyl and Ketamine Hcl, by gender? *:

female:

  1. Pneumonia
  2. Status epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure)
  3. Angioedema (rapid swelling of the dermis)
  4. Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
  5. Ammonia increased
  6. Clostridial infection (infectious conditions by clostridium bacteria)
  7. Confusional state
  8. Crepitations (noises are produced by the rubbing of parts one against the other)
  9. Depressed level of consciousness
  10. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)

male:

  1. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  2. Jugular vein thrombosis (clot in jugular vein)
  3. Arterial occlusive disease (slow process through which arteries throughout the body become progressively narrowed and eventually completely blocked)
  4. Bradycardia (abnormally slow heart action)
  5. Cardiac failure
  6. Coma (state of unconsciousness lasting more than six hours)
  7. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  8. Death
  9. Depressed level of consciousness
  10. Depression

What are the common drug interactions of Flagyl and Ketamine Hcl, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Respiratory failure (inadequate gas exchange by the respiratory system)
  2. Acute pulmonary oedema (sudden deposit of fluid in the lung))
  3. Agitation (state of anxiety or nervous excitement)
  4. Amaurosis (partial or total blindness without visible change in the eye)
  5. Bradycardia (abnormally slow heart action)
  6. Cardiac failure
  7. Coma (state of unconsciousness lasting more than six hours)
  8. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  9. Depressed level of consciousness
  10. Depression

10-19:

  1. Ammonia increased
  2. Confusional state
  3. Depressed level of consciousness
  4. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  5. Transaminases increased

20-29:

  1. Propofol infusion syndrome
  2. Renal failure acute (rapid kidney dysfunction)
  3. Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)

30-39:

  1. Anaesthetic complication
  2. Malaise (a feeling of general discomfort or uneasiness)
  3. Pancreatitis (inflammation of pancreas)
  4. Skin disorder (skin disease)
  5. Syncope vasovagal (malfunction in the parts of the nervous system leads to consciousness with an inability to maintain postural tone)

40-49:

  1. Streptococcal infection

50-59:

n/a

60+:

  1. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  2. Jugular vein thrombosis (clot in jugular vein)
  3. Mitral valve incompetence (inefficient heart valve)
  4. Renal failure (kidney dysfunction)
  5. Renal impairment (severely reduced kidney function)
  6. Renal injury (kidney injury)
  7. Stress
  8. Thrombosis (formation of a blood clot inside a blood vessel)
  9. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  10. Anxiety

What are the existing conditions these people have? *

  1. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 3 people, 27.27%
  2. Stress And Anxiety: 1 person, 9.09%
  3. Lambert-Eaton Syndrome (this means your immune system mistakenly targets healthy cells and tissues in the body): 1 person, 9.09%
  4. Birth Control: 1 person, 9.09%
  5. Fever: 1 person, 9.09%
  6. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 9.09%
  7. Hepatic Encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure): 1 person, 9.09%
  8. Hypervolaemia (abnormally increased volume of blood): 1 person, 9.09%
  9. Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking): 1 person, 9.09%
  10. Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Flagyl and Ketamine hcl?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Flagyl and Ketamine hcl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Flagyl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Ketamine hcl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Flagyl and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ketamine hcl and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on metronidazole and ketamine hydrochloride (the active ingredients of Flagyl and Ketamine hcl, respectively), and Flagyl and Ketamine hcl (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: