Flagyl and Ketoprofen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Flagyl (metronidazole) and Ketoprofen (ketoprofen). Common drug interactions include leukopenia among females and tinnitus among males.

The phase IV clinical study analyzes what interactions people have when they take Flagyl and Ketoprofen. It is created by eHealthMe based on reports of 47 people who take the same drugs from the FDA, and is updated regularly.

What is Flagyl?

Flagyl has active ingredients of metronidazole. It is often used in vaginitis bacterial. eHealthMe is studying from 25,897 Flagyl users. Check the latest studies of Flagyl.

What is Ketoprofen?

Ketoprofen has active ingredients of ketoprofen. It is often used in pain. eHealthMe is studying from 15,048 Ketoprofen users. Check the latest studies of Ketoprofen.

On Jul, 28, 2026

47 people who take Flagyl and Ketoprofen together, and have interactions are studied.

Flagyl and Ketoprofen drug interactions.

What are the common drug interactions of Flagyl and Ketoprofen, by gender? *:

female:

Leukopenia (less number of white blood cells in blood)
Neutropenia (an abnormally low number of neutrophils)
Pruritus (severe itching of the skin)
Syncope (loss of consciousness with an inability to maintain postural tone)
Urticaria (rash of round, red welts on the skin that itch intensely)
Vomiting
Malaise (a feeling of general discomfort or uneasiness)
Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
Arrhythmia (irregular heartbeat)
Bradyphrenia (neurological term referring to the slowness of thought common to many disorders of the brain)

male:

Tinnitus (a ringing in the ears)
Hypertension (high blood pressure)
Gastric ulcer helicobacter (ulcer caused by helicobacter bacteria)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Emotional distress
Necrotising enterocolitis neonatal (life threatening infection of intestine in newborn baby)
Neonatal respiratory distress syndrome (a serious medical condition where a newborn baby's lungs cannot provide their body with enough oxygen)
Osteoporosis (bones weak and more likely to break)
Rib fracture

What are the common drug interactions of Flagyl and Ketoprofen, by age (0-1 to 60+)? *:

0-1:

Necrotising enterocolitis neonatal (life threatening infection of intestine in newborn baby)
Neonatal respiratory distress syndrome (a serious medical condition where a newborn baby's lungs cannot provide their body with enough oxygen)
Bronchopulmonary dysplasia (chronic lung disorder in infants - enlargement of an organ or tissue by the proliferation of cells of an abnormal type)
Cerebral haemorrhage (bleeding within the brain)
Premature baby
Abortion missed (delayed or silent miscarriage)
Cerebral disorder (brain disease)
Cerebral haemorrhage neonatal (bleeding in brain of baby of less than 1 month age)
Colitis ulcerative (inflammation of colon with ulcer)
Drug exposure during pregnancy

2-9:

n/a

10-19:

n/a

20-29:

Drug exposure during pregnancy

30-39:

Confusional state
Headache (pain in head)
Hepatitis acute
Memory impairment
Rash scarlatiniform (rash 3-5mm size)
Vertigo

40-49:

Blood creatinine increased
Gastric ulcer helicobacter (ulcer caused by helicobacter bacteria)
Hypertension (high blood pressure)
Osteonecrosis (death of bone)
Angina pectoris (chest pain due to ischemia of the heart muscle)
Pain in limb
Rash
Rash erythematous (redness of the skin)
Rash generalised (rash on most of body parts)
Sweating increased (excess sweating)

50-59:

General physical health deterioration (weak health status)
Hypersomnia (excessive daytime sleepiness (eds))
Hyperthyroidism (over activity of the thyroid gland)
Hypokalaemia (low potassium)
Inflammation
Insomnia (sleeplessness)
Malaise (a feeling of general discomfort or uneasiness)
Overdose
Renal disorder (kidney disease)
Renal impairment (severely reduced kidney function)

60+:

Pneumonia
Rash
Urticaria (rash of round, red welts on the skin that itch intensely)
Vomiting
Vertigo
Arrhythmia (irregular heartbeat)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Cardiac failure
Cardiac failure congestive
Cataract (clouding of the lens inside the eye)

What are the existing conditions these people have? *

Urinary Tract Infection: 5 people, 10.64%
Multiple Myeloma (cancer of the plasma cells): 4 people, 8.51%
Hiv Infection: 4 people, 8.51%
Prostatitis (inflammation of the prostate gland): 3 people, 6.38%
Perioperative Analgesia: 3 people, 6.38%
Otitis Externa (external ear infection): 3 people, 6.38%
Lung Disorder (lung disease): 3 people, 6.38%
Diabetes: 3 people, 6.38%
Anaemia (lack of blood): 3 people, 6.38%
Adverse Event: 3 people, 6.38%

* Approximation only. Some reports may have incomplete information.

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