Flagyl and Tadalafil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Flagyl (metronidazole) and Tadalafil (tadalafil). Common drug interactions include drug hypersensitivity among females and heart rate increased among males.

The phase IV clinical study analyzes what interactions people have when they take Flagyl and Tadalafil. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Flagyl?

Flagyl has active ingredients of metronidazole. It is often used in vaginitis bacterial. eHealthMe is studying from 25,897 Flagyl users. Check the latest studies of Flagyl.

What is Tadalafil?

Tadalafil has active ingredients of tadalafil. It is often used in erection problems. eHealthMe is studying from 25,548 Tadalafil users. Check the latest studies of Tadalafil.

On Jul, 26, 2026

14 people who take Flagyl and Tadalafil together, and have interactions are studied.

What are the common drug interactions of Flagyl and Tadalafil, by gender? *:

female:

Drug hypersensitivity
Oedema peripheral (superficial swelling)
Abdominal discomfort
Abdominal distension
Abdominal pain lower
Arteritis (inflammation of the walls of arteries)
Arthralgia (joint pain)
Arthritis infective (purulent invasion of a joint by an infectious agent which produces arthritis)
Arthropathy
Bone loss

male:

Heart rate increased
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Intestinal obstruction
Nausea (feeling of having an urge to vomit)
Neutropenia (an abnormally low number of neutrophils)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Pouchitis (inflammatory bowel disease)
Rectal haemorrhage (bleeding from anus)
Palpitations (feelings or sensations that your heart is pounding or racing)
Pyrexia (fever)

What are the common drug interactions of Flagyl and Tadalafil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Abdominal discomfort
Abdominal distension
Abdominal pain lower
Arteritis (inflammation of the walls of arteries)
Arthralgia (joint pain)
Arthritis infective (purulent invasion of a joint by an infectious agent which produces arthritis)
Arthropathy
Bone loss
Bone pain
Chills (felling of cold)

40-49:

Heart rate increased
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Palpitations (feelings or sensations that your heart is pounding or racing)

50-59:

Acute respiratory failure
Cardiogenic shock (inadequate circulation of blood)
Fungaemia (fungi circulate in the blood)
Lethargy (tiredness)
Pneumonia
Septic shock (shock due to blood infection)

60+:

Pyrexia (fever)
Abscess neck (neck abscesses)
Cor pulmonale (enlargement of the right ventricle of the heart)
Cough
Dehydration (dryness resulting from the removal of water)
Dyspnoea exertional (breathlessness or shortness of breath)
Fall
Fluid overload (too much fluid in the blood)
Hypotension (abnormally low blood pressure)
Intestinal obstruction

What are the existing conditions these people have? *

Constipation: 3 people, 21.43%
Pain: 3 people, 21.43%
Fever: 3 people, 21.43%
Thyroid Diseases: 2 people, 14.29%
Hypokalemia (low potassium): 2 people, 14.29%
Anaesthesia: 2 people, 14.29%
Celiac Disease - Sprue (a disease of the small intestine): 2 people, 14.29%
Cytokine Release Syndrome (immediate complication occurring with the use of anti-t cell antibody infusions): 2 people, 14.29%
Dyslipidaemia (abnormal amount of lipids): 2 people, 14.29%
Enlarged Prostate: 2 people, 14.29%

* Approximation only. Some reports may have incomplete information.

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