Flavin and Folate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Flavin (riboflavin (vitamin b2)) and Folate (folic acid). Common drug interactions include hypoaesthesia among females and spinal osteoarthritis among males.

The phase IV clinical study analyzes what interactions people have when they take Flavin and Folate. It is created by eHealthMe based on reports of 45 people who take the same drugs from the FDA, and is updated regularly.

What is Flavin?

Flavin has active ingredients of riboflavin (vitamin b2). eHealthMe is studying from 2,870 Flavin users. Check the latest studies of Flavin.

What is Folate?

Folate has active ingredients of folic acid. It is often used in rheumatoid arthritis. eHealthMe is studying from 6,546 Folate users. Check the latest studies of Folate.

On Jul, 08, 2026

45 people who take Flavin and Folate together, and have interactions are studied.

What are the common drug interactions of Flavin and Folate, by gender? *:

female:

Hypoaesthesia (reduced sense of touch or sensation)
Hypophagia (reduced food intake)
Hypovolaemia (a decreased volume of circulating blood in the body)
Hypoxia (low oxygen in tissues)
Ischaemic hepatitis (decreased blood supply to the liver resulting in injury to liver cells)
Malaise (a feeling of general discomfort or uneasiness)
Muscular weakness (muscle weakness)
Oedema (fluid collection in tissue)
Oesophageal stenosis (narrowing of oesophagus)
Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)

male:

Spinal osteoarthritis (joint cartilage loss in spine)
Therapeutic response decreased (less preventive response)
Rash
Abasia (inability to walk)
Diarrhoea
Fall
Gastrointestinal infection (infection of stomach and intestine)
Vomiting
Mobility decreased (ability to move is reduced)
Arthropathy

What are the common drug interactions of Flavin and Folate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Abdominal discomfort
Aggression
Brain injury
Underweight

10-19:

Kidney infection

20-29:

Haemorrhage (bleeding)
Herpes zoster
Muscle spasms (muscle contraction)
Post herpetic neuralgia (neuralgia caused by the varicella zoster virus)
Uterine pain

30-39:

Pruritus (severe itching of the skin)
Rash
Injection site rash
Vulvovaginal pruritus (vulvovaginal severe itching)

40-49:

Drug ineffective
Fatigue (feeling of tiredness)
Spinal osteoarthritis (joint cartilage loss in spine)
Therapeutic response decreased (less preventive response)
Tooth disorder (tooth disease)
Abdominal pain upper
Arthralgia (joint pain)
Burning sensation
Cardiac disorder
Constipation

50-59:

Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Injection site pain
Injection site pruritus (severe itching at injection site)
Injection site swelling
Injection site urticaria (rash of round, red welts on the skin at injection site)
Iodine deficiency
Lip swelling
Migraine (headache)
Muscle spasms (muscle contraction)
Muscular weakness (muscle weakness)

60+:

Vomiting
Diarrhoea
Constipation
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
Dizziness
Dyspepsia (indigestion)
Fatigue (feeling of tiredness)
Haemoglobin increased
Loss of consciousness
Mean cell volume increased (more than normal average red blood cell volume)

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 12 people, 26.67%
Migraine (headache): 9 people, 20.00%
Nausea (feeling of having an urge to vomit): 6 people, 13.33%
Anaemia (lack of blood): 5 people, 11.11%
Rashes (redness): 4 people, 8.89%
Nosebleed (bleeding from nose): 4 people, 8.89%
Malabsorption (a state arising from abnormality in absorption of food nutrients across the gastrointestinal (gi) tract): 4 people, 8.89%
Herpes Simplex (herpes simplex is a common viral infection): 4 people, 8.89%
Gastrointestinal Infection (infection of stomach and intestine): 4 people, 8.89%
Diarrhea: 4 people, 8.89%

* Approximation only. Some reports may have incomplete information.

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