Flecainide acetate and Duragesic-100 drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Flecainide acetate (flecainide acetate) and Duragesic-100 (fentanyl). Common drug interactions include skin necrosis among females and dizziness among males.

The phase IV clinical study analyzes what interactions people have when they take Flecainide acetate and Duragesic-100. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Flecainide acetate?

Flecainide acetate has active ingredients of flecainide acetate. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 7,176 Flecainide acetate users. Check the latest studies of Flecainide acetate.

What is Duragesic-100?

Duragesic-100 has active ingredients of fentanyl. It is often used in pain. eHealthMe is studying from 19,509 Duragesic-100 users. Check the latest studies of Duragesic-100.

On Jul, 28, 2026

20 people who take Flecainide acetate and Duragesic-100 together, and have interactions are studied.

Flecainide acetate and Duragesic-100 drug interactions.

What are the common drug interactions of Flecainide Acetate and Duragesic-100, by gender? *:

female:

Skin necrosis (skin damage)
Dermatitis psoriasiform (large white or silver flakes on the skin)
Leukocytoclastic vasculitis (inflammation of small blood vessels (usually post-capillary venules in the dermis), characterized by palpable purpura)
Delirium (wild excitement)
Hallucination (an experience involving the perception of something not present)
Aortic valve disease
C-reactive protein increased
Diabetic microangiopathy (small blood vessels of the body are damaged due to diabetes)
Haemoglobin decreased
Microalbuminuria (albumin into the urine)

male:

Dizziness
Fall
Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
Dehydration (dryness resulting from the removal of water)
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Hallucination, visual (seeing things that aren't there)
Inguinal hernia strangulated (hernia in which a loop of intestine enters the inguinal canal with blood supply damaged)
Overdose
Oxygen saturation decreased
Renal failure acute (rapid kidney dysfunction)

What are the common drug interactions of Flecainide Acetate and Duragesic-100, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Skin necrosis (skin damage)
Dermatitis psoriasiform (large white or silver flakes on the skin)
Weight decreased
Delirium (wild excitement)
Hallucination (an experience involving the perception of something not present)
Aortic valve disease
C-reactive protein increased
Chills (felling of cold)
Confusional state
Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)

What are the existing conditions these people have? *

Diabetes: 5 people, 25.00%
Multiple Myeloma (cancer of the plasma cells): 4 people, 20.00%
High Blood Pressure: 4 people, 20.00%
Hepatic Neoplasm Malignant (liver cancer): 3 people, 15.00%
Bone Pain: 3 people, 15.00%
Wolff-Parkinson-White Syndrome (a heart condition in which there is an abnormal extra electrical pathway of the heart): 2 people, 10.00%
Nausea (feeling of having an urge to vomit): 2 people, 10.00%
Lung Neoplasm Malignant (cancer tumour of lung): 2 people, 10.00%
Lung Cancer - Non-Small Cell (lung cancer): 2 people, 10.00%
High Blood Cholesterol: 2 people, 10.00%

* Approximation only. Some reports may have incomplete information.

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