Flecainide acetate and Exforge drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Flecainide acetate (flecainide acetate) and Exforge (amlodipine besylate; valsartan). Common drug interactions include arthralgia among females and blood creatine phosphokinase increased among males.

The phase IV clinical study analyzes what interactions people have when they take Flecainide acetate and Exforge. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Flecainide acetate?

Flecainide acetate has active ingredients of flecainide acetate. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 7,176 Flecainide acetate users. Check the latest studies of Flecainide acetate.

What is Exforge?

Exforge has active ingredients of amlodipine besylate; valsartan. It is often used in high blood pressure. eHealthMe is studying from 13,350 Exforge users. Check the latest studies of Exforge.



On Jul, 08, 2026

18 people who take Flecainide acetate and Exforge together, and have interactions are studied.

Flecainide acetate and Exforge drug interactions.

What are the common drug interactions of Flecainide Acetate and Exforge, by gender? *:

female:

  1. Arthralgia (joint pain)
  2. Asthenia (weakness)
  3. Back pain
  4. Balance disorder
  5. Blood calcium increased
  6. Bone pain
  7. Dizziness
  8. Eye disorder
  9. Fall
  10. Fatigue (feeling of tiredness)

male:

  1. Blood creatine phosphokinase increased
  2. Atrioventricular block (heart block)
  3. Cardiac failure congestive
  4. Cardiac fibrillation (uncontrolled muscle contraction of heart)
  5. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  6. Dehydration (dryness resulting from the removal of water)
  7. Device related infection
  8. Erysipelas (bacterial skin infection)
  9. Face oedema (swelling of face)
  10. Failure to thrive (inadequate weight gain and physical growth in children)

What are the common drug interactions of Flecainide Acetate and Exforge, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

  1. Blood creatine phosphokinase increased
  2. Arthralgia (joint pain)
  3. Fatigue (feeling of tiredness)
  4. Head injury
  5. Inner ear disorder
  6. Limb asymmetry (consistent task discrepancy between the two lower limbs)
  7. Motion sickness (travel sickness)
  8. Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)
  9. Muscle spasms (muscle contraction)
  10. Musculoskeletal discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves)

What are the existing conditions these people have? *

  1. High Blood Pressure: 4 people, 22.22%
  2. Osteoporosis (bones weak and more likely to break): 3 people, 16.67%
  3. Enlarged Prostate: 2 people, 11.11%
  4. Arrhythmias (irregular heartbeat): 2 people, 11.11%
  5. Pain: 1 person, 5.56%
  6. Malignant Melanoma (skin cancer rises from melancytes): 1 person, 5.56%
  7. Low Density Lipoprotein Increased (cholesterol increased in blood): 1 person, 5.56%
  8. High Blood Cholesterol: 1 person, 5.56%
  9. Gastroesophageal Cancer: 1 person, 5.56%
  10. Diabetes: 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Flecainide acetate and Exforge?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Flecainide acetate and Exforge:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Flecainide acetate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Exforge:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Flecainide acetate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Exforge and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on flecainide acetate and amlodipine besylate; valsartan (the active ingredients of Flecainide acetate and Exforge, respectively), and Flecainide acetate and Exforge (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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