Flecainide acetate and Melatonin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Flecainide acetate (flecainide acetate) and Melatonin (melatonin). Common drug interactions include lymphoedema among females and hallucination among males.

The phase IV clinical study analyzes what interactions people have when they take Flecainide acetate and Melatonin. It is created by eHealthMe based on reports of 74 people who take the same drugs from the FDA, and is updated regularly.

What is Flecainide acetate?

Flecainide acetate has active ingredients of flecainide acetate. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 7,176 Flecainide acetate users. Check the latest studies of Flecainide acetate.

What is Melatonin?

Melatonin has active ingredients of melatonin. It is often used in insomnia. eHealthMe is studying from 56,212 Melatonin users. Check the latest studies of Melatonin.

On Jul, 17, 2026

74 people who take Flecainide acetate and Melatonin together, and have interactions are studied.

Flecainide acetate and Melatonin drug interactions.

What are the common drug interactions of Flecainide Acetate and Melatonin, by gender? *:

female:

Lymphoedema (localized fluid retention and tissue swelling)
Peripheral swelling
Pleural effusion (water on the lungs)
Pneumonia fungal
Pseudomonas infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa)
Pulmonary vascular disorder
Rib fracture
Somnambulism (sleep walking)
Thyroid cyst
Weight increased

male:

Hallucination (an experience involving the perception of something not present)
Fatigue (feeling of tiredness)
Renal disorder (kidney disease)
Confusional state
Anxiety
Blood pressure increased
Dizziness
Infection
Neuropathy peripheral (surface nerve damage)
Asthenia (weakness)

What are the common drug interactions of Flecainide Acetate and Melatonin, by age (0-1 to 60+)? *:

0-1:

Weight decreased

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Cardiac aneurysm (a condition that can occur after a myocardial infarction due to the inadequate resistance of the new scar tissue to the systolic pressure)
Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
Infection
Multi-organ failure (multisystem organ failure)
Non-hodgkin's lymphoma (malignant (cancer) cells form in the lymph system)
Post procedural infection
Renal failure (kidney dysfunction)
Sepsis (a severe blood infection that can lead to organ failure and death)

40-49:

Infusion site reaction
Malaise (a feeling of general discomfort or uneasiness)
Nasopharyngitis (inflammation of the nasopharynx)
Nephrolithiasis (calculi in the kidneys)
Osteoporosis (bones weak and more likely to break)
Pain
Pericardial effusion (fluid around the heart)
Pyrexia (fever)
Renal impairment (severely reduced kidney function)
Tibia fracture (fracture of lower leg bone)

50-59:

Anxiety
Drug ineffective
Hyperthyroidism (over activity of the thyroid gland)
Panic attack
Pharyngitis (inflammation of the pharynx, causing a sore throat)

60+:

Fatigue (feeling of tiredness)
Nausea (feeling of having an urge to vomit)
Swelling
Diarrhoea
Anxiety
Burning sensation
Infusion related reaction
Neuropathy peripheral (surface nerve damage)
Pruritus (severe itching of the skin)
Rash

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 20 people, 27.03%
Multiple Myeloma (cancer of the plasma cells): 6 people, 8.11%
Primary Immunodeficiency Syndrome: 4 people, 5.41%
Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 4 people, 5.41%
High Blood Cholesterol: 4 people, 5.41%

* Approximation only. Some reports may have incomplete information.

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