Flector and Hydramine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Flector (diclofenac epolamine) and Hydramine (diphenhydramine hydrochloride). Common drug interactions include sinusitis among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Flector and Hydramine. It is created by eHealthMe based on reports of 46 people who take the same drugs from the FDA, and is updated regularly.

What is Flector?

Flector has active ingredients of diclofenac epolamine. It is often used in pain. eHealthMe is studying from 5,112 Flector users. Check the latest studies of Flector.

What is Hydramine?

Hydramine has active ingredients of diphenhydramine hydrochloride. It is often used in insomnia. eHealthMe is studying from 114,900 Hydramine users. Check the latest studies of Hydramine.

On Aug, 08, 2026

46 people who take Flector and Hydramine together, and have interactions are studied.

Flector and Hydramine drug interactions.

What are the common drug interactions of Flector and Hydramine, by gender? *:

female:

Sinusitis (inflammation of sinus)
Fall
Headache (pain in head)
Infusion related reaction
Anxiety
Cough
Urinary tract infection
Rash
Skin irritation
Vulvovaginal pain

male:

Fatigue (feeling of tiredness)
Sinusitis (inflammation of sinus)
Fear
Mobility decreased (ability to move is reduced)
Non-hodgkin's lymphoma (malignant (cancer) cells form in the lymph system)
Quality of life decreased
Vascular occlusion (sudden blockage of a blood vessel, usually with a clot)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Chronic kidney disease

What are the common drug interactions of Flector and Hydramine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Chronic kidney disease
Decreased activity
Depression
Emotional distress
Fatigue (feeling of tiredness)
Fear
Mobility decreased (ability to move is reduced)
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)

60+:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Back injury
Fall
Fibromyalgia (a long-term condition which causes pain all over the body)
Gastritis (inflammation of stomach)
Headache (pain in head)
Herpes zoster
Infusion related reaction
Infusion site bruising

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 33 people, 71.74%
Stress And Anxiety: 3 people, 6.52%
Immune System Disorder: 3 people, 6.52%
Hypersensitivity: 3 people, 6.52%
Hiv Infection: 3 people, 6.52%
Bacterial Infection: 3 people, 6.52%

* Approximation only. Some reports may have incomplete information.

Do you take Flector and Hydramine?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously