Flolan and Percocet drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Flolan (epoprostenol sodium) and Percocet (acetaminophen; oxycodone hydrochloride). Common drug interactions include diarrhoea among females and catheter related complication among males.

The phase IV clinical study analyzes what interactions people have when they take Flolan and Percocet. It is created by eHealthMe based on reports of 49 people who take the same drugs from the FDA, and is updated regularly.

What is Flolan?

Flolan has active ingredients of epoprostenol sodium. eHealthMe is studying from 10,067 Flolan users. Check the latest studies of Flolan.

What is Percocet?

Percocet has active ingredients of acetaminophen; oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 119,838 Percocet users. Check the latest studies of Percocet.

On Jul, 08, 2026

49 people who take Flolan and Percocet together, and have interactions are studied.

What are the common drug interactions of Flolan and Percocet, by gender? *:

female:

Diarrhoea
Dyspnoea (difficult or laboured respiration)
Pneumonia
Vomiting
Gallbladder disorder
Syncope (loss of consciousness with an inability to maintain postural tone)
Cough
Malaise (a feeling of general discomfort or uneasiness)
Muscle spasms (muscle contraction)
Nausea (feeling of having an urge to vomit)

male:

Catheter related complication
Oedema peripheral (superficial swelling)
Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
Hepatic failure (liver failure)
Oxygen saturation decreased
Pain in jaw
Photophobia (extreme sensitivity to light)
Abdominal neoplasm (cancer of the stomach)
Chronic hepatic failure (long lasting liver failure)
Death

What are the common drug interactions of Flolan and Percocet, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Diarrhoea
Dyspnoea (difficult or laboured respiration)
Vomiting
Abdominal pain
Burning sensation
Central line infection (infection by central line in icu)
Chest pain
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)

40-49:

Catheter related complication
Cough
Diarrhoea
Flushing (the warm, red condition of human skin)
Gastroenteritis (inflammation of stomach and intestine)
Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Nausea (feeling of having an urge to vomit)
Vomiting
Abdominal pain

50-59:

Intestinal mass
Loss of consciousness
Nerve compression
Dyspnoea (difficult or laboured respiration)
Pneumonia
Diarrhoea
Gallbladder disorder
Syncope (loss of consciousness with an inability to maintain postural tone)
Hospitalisation
Oxygen saturation decreased

60+:

Contusion (a type of hematoma of tissue in which capillaries)
Erythema (redness of the skin)
Headache (pain in head)
Pain in jaw
Diarrhoea
Dyspnoea (difficult or laboured respiration)
Nausea (feeling of having an urge to vomit)
Oxygen saturation decreased
Retching (strong involuntary effort to vomit)
Fatigue (feeling of tiredness)

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 33 people, 67.35%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 12 people, 24.49%

* Approximation only. Some reports may have incomplete information.

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