Flomax and Zoledronic drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Flomax (tamsulosin hydrochloride) and Zoledronic (zoledronic acid). Common drug interactions include constipation among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Flomax and Zoledronic. It is created by eHealthMe based on reports of 71 people who take the same drugs from the FDA, and is updated regularly.

What is Flomax?

Flomax has active ingredients of tamsulosin hydrochloride. It is often used in enlarged prostate. eHealthMe is studying from 52,865 Flomax users. Check the latest studies of Flomax.

What is Zoledronic?

Zoledronic has active ingredients of zoledronic acid. eHealthMe is studying from 29,812 Zoledronic users. Check the latest studies of Zoledronic.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 17, 2026

71 people who take Flomax and Zoledronic together, and have interactions are studied.

Flomax and Zoledronic drug interactions.

What are the common drug interactions of Flomax and Zoledronic, by gender? *:

female:

  1. Constipation
  2. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  3. Asthenia (weakness)
  4. Asthma
  5. Chills (felling of cold)
  6. Fall
  7. Myalgia (muscle pain)
  8. Pyrexia (fever)

male:

  1. Fatigue (feeling of tiredness)
  2. Anaemia (lack of blood)
  3. Dyspepsia (indigestion)
  4. Eructation (release of gas from the digestive tract)
  5. Headache (pain in head)
  6. Infection
  7. Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
  8. Pain
  9. Pleural effusion (water on the lungs)
  10. Throat irritation

What are the common drug interactions of Flomax and Zoledronic, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Hypersensitivity
  2. Blood creatinine increased
  3. Dizziness
  4. Headache (pain in head)
  5. Lupus nephritis (a chronic inflammatory autoimmune disorder that may affect kidney tissue)
  6. Proteinuria (presence of protein in the urine)
  7. Pruritus (severe itching of the skin)
  8. Rash
  9. Renal impairment (severely reduced kidney function)
  10. Viral infection

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Malaise (a feeling of general discomfort or uneasiness)
  2. Mouth ulceration (mouth ulcers)
  3. Oral discomfort (pain or irritation in mouth)
  4. Salivary hypersecretion (excess saliva secretion)
  5. Activities of daily living impaired
  6. Glossodynia (a burning or painful sensation in the tongue)
  7. Lip dry

50-59:

  1. Chest discomfort
  2. Erythema (redness of the skin)
  3. Feeling hot
  4. Flushing (the warm, red condition of human skin)
  5. Nausea (feeling of having an urge to vomit)
  6. Visual impairment

60+:

  1. Anaemia (lack of blood)
  2. Pneumonia
  3. Infection
  4. Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
  5. Pleural effusion (water on the lungs)
  6. Throat irritation
  7. Chills (felling of cold)
  8. Pyrexia (fever)
  9. Anxiety
  10. Dyspnoea (difficult or laboured respiration)

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 47 people, 66.20%
  2. Prostate Cancer Metastatic: 9 people, 12.68%
  3. Pain: 8 people, 11.27%
  4. Metastases To Bone (cancer spreads to bone): 6 people, 8.45%
  5. Nausea (feeling of having an urge to vomit): 5 people, 7.04%
  6. Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 5 people, 7.04%
  7. Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 5 people, 7.04%
  8. Pollakiuria (abnormally frequent passage of relatively small quantities or urine): 4 people, 5.63%
  9. Haemorrhoids (a swollen vein or group of veins in the region of the anus): 4 people, 5.63%
  10. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 5.63%

* Approximation only. Some reports may have incomplete information.

Do you take Flomax and Zoledronic?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Flomax and Zoledronic:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Flomax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Zoledronic:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Flomax and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Zoledronic and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on tamsulosin hydrochloride and zoledronic acid (the active ingredients of Flomax and Zoledronic, respectively), and Flomax and Zoledronic (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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