Florinef and Evista drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Florinef (fludrocortisone acetate) and Evista (raloxifene hydrochloride). Common drug interactions include arthralgia among females.

The phase IV clinical study analyzes what interactions people have when they take Florinef and Evista. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Florinef?

Florinef has active ingredients of fludrocortisone acetate. It is often used in addison's disease. eHealthMe is studying from 3,834 Florinef users. Check the latest studies of Florinef.

What is Evista?

Evista has active ingredients of raloxifene hydrochloride. It is often used in osteoporosis. eHealthMe is studying from 25,891 Evista users. Check the latest studies of Evista.

On Jul, 09, 2026

26 people who take Florinef and Evista together, and have interactions are studied.

What are the common drug interactions of Florinef and Evista, by gender? *:

female:

Arthralgia (joint pain)
Clamminess (moist, sticky, and cold to the touch)
Urinary tract infection
Activities of daily living impaired
Anxiety
Asthenia (weakness)
Balance disorder
Blood creatinine increased
Blood sodium decreased
Blood urea increased

male:

n/a

What are the common drug interactions of Florinef and Evista, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Back pain
Muscle spasms (muscle contraction)
Pyrexia (fever)
Urinary tract infection

50-59:

Clamminess (moist, sticky, and cold to the touch)
Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Pain in jaw
Pain in limb
Palpitations (feelings or sensations that your heart is pounding or racing)
Acute circulatory failure (shock)
Arthralgia (joint pain)
Groin pain
Pain in extremity

60+:

Femur fracture
Loss of consciousness
Hypoglycaemia (deficiency of glucose in the bloodstream)
Hypokalaemia (low potassium)
Thrombophlebitis deep (deep swelling (inflammation) of a vein caused by a blood clot)
Activities of daily living impaired
Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
Anxiety
Asthenia (weakness)
Asthma

What are the existing conditions these people have? *

Osteopenia (a condition where bone mineral density is lower than normal): 3 people, 11.54%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 3 people, 11.54%
Orthostatic Hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up): 2 people, 7.69%
Hypersensitivity: 2 people, 7.69%
High Blood Cholesterol: 2 people, 7.69%

* Approximation only. Some reports may have incomplete information.

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