Florinef and Lactulose drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Florinef (fludrocortisone acetate) and Lactulose (lactulose). Common drug interactions include breath odour among females and pruritus among males.

The phase IV clinical study analyzes what interactions people have when they take Florinef and Lactulose. It is created by eHealthMe based on reports of 57 people who take the same drugs from the FDA, and is updated regularly.

What is Florinef?

Florinef has active ingredients of fludrocortisone acetate. It is often used in addison's disease. eHealthMe is studying from 3,834 Florinef users. Check the latest studies of Florinef.

What is Lactulose?

Lactulose has active ingredients of lactulose. It is often used in constipation. eHealthMe is studying from 46,960 Lactulose users. Check the latest studies of Lactulose.

On Aug, 12, 2026

57 people who take Florinef and Lactulose together, and have interactions are studied.

Florinef and Lactulose drug interactions.

What are the common drug interactions of Florinef and Lactulose, by gender? *:

female:

Breath odour
Cataract (clouding of the lens inside the eye)
Chest pain
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
Contusion (a type of hematoma of tissue in which capillaries)
Dental caries
Dyspnoea (difficult or laboured respiration)
Dysuria (painful or difficult urination)

male:

Pruritus (severe itching of the skin)
Rash erythematous (redness of the skin)
Pneumonia
White blood cell count decreased
Azotaemia (excess of urea or other nitrogenous compounds in the blood)
Dehydration (dryness resulting from the removal of water)
Fatigue (feeling of tiredness)
Haemoglobin decreased
Hepatic failure (liver failure)
Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)

What are the common drug interactions of Florinef and Lactulose, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Abdominal discomfort
Dizziness
Eating disorder
Fatigue (feeling of tiredness)
Irritability
Loss of consciousness
Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
Pallor
Partner stress
Suicide attempt

50-59:

Osteoporosis (bones weak and more likely to break)
Anaemia (lack of blood)
Blood creatinine increased
Coagulopathy (blood's ability to clot is impaired)
Disease progression
Dyspnoea (difficult or laboured respiration)
Dysuria (painful or difficult urination)
General physical health deterioration (weak health status)
Haematuria (presence of blood in urine)
Hyperkalaemia (damage to or disease of the kidney)

60+:

Headache (pain in head)
Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
Actinomycosis (infection that causes sores, or abscesses)
Anxiety
Atelectasis (partial or complete collapse of the lung)
Bacterial infection
Bone disorder
Breath odour
Cataract (clouding of the lens inside the eye)
Chest pain

What are the existing conditions these people have? *

Stress And Anxiety: 13 people, 22.81%
Metastases To Bone (cancer spreads to bone): 10 people, 17.54%
Parkinson's Disease: 7 people, 12.28%
Infection: 5 people, 8.77%
Pain: 4 people, 7.02%
Orthostatic Hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up): 4 people, 7.02%
Multiple Myeloma (cancer of the plasma cells): 4 people, 7.02%
Depression: 4 people, 7.02%
Cough: 4 people, 7.02%
Sarcoma (rare cancers that develop in the muscle, bone, nerves, cartilage, tendons, blood vessels and the fatty and fibrous tissues): 3 people, 5.26%

* Approximation only. Some reports may have incomplete information.

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